Biomedical use of dendrimers
13th -14th March 2008 at 09:15 in the Benzon Auditorium
The Faculty of Pharmaceutical Sciences, Universitetsparken 2, 2100 Copenhagen
Program
Thursday 13th March 2008
| 09:15 - 09.30 | Coffee |
| 09:30 - 09:40 | Opening remarks |
| 09:40 - 10:25 | Dendrimers in biomedical applications |
| 10:35 - 11:20 | Dendritic amplification - from nanomaterials to nanomedicine Professor David Smith, Department of Chemistry, University of York, UK |
| 11:30 - 11.55 | Coffee |
| 11:55 - 12:40 | Structural characterization of dendrimers Professor Kell Mortensen, Faculty of Life Sciences, University of Copenhagen |
| 12:50 - 13:40 | Lunch |
| 13:40 - 14:25 | Biophysical methodologies to characterize dendrimers for drug delivery Dr. Francoise Bonneté, Molecular Engineering and Functional Materials, INaM-CNRS, Aix-Marseille University, France |
| 14:35 - 15:20 | Glycodendrimers as tools to investigate mechanisms of bacterial adhesion Profesor Thisbe K. Lindhorst, Otto Diels Institute of Organic Chemistry, Christiana Albertina University of Kiel, Germany |
| 15:30 - 15:45 | Coffee |
| 15:45 - 16:30 | Affinity of dendrimers for proteins and peptides - biomedical implications Dr. Barbara Klajnert, Department of General Biophysics, University of Lódz, Poland |
Friday 14th March 2008
| 08:30 - 09:00 | Coffee |
| 09:00 - 09:45 | Use of dendrimers in drug delivery applications in order to overcome biological barriers Professor Antony D'Emanuele, Faculty of Science and Technology: Pharmacy, School of Pharmacy and Pharmaceutical Sciences, University of Central Lancashire, UK |
| 09:55 - 10:40 | Dendrimers for non-viral delivery of RNA Dr. Ling Peng, Department of Chemistry, National Center for Scientific Research (CRMC-N), Marseille, France |
| 10:50 - 11:05 | Coffee |
| 11:05 - 11:25 | Dendrimers for in vitro delivery of siRNA PhD student Linda Boye Jensen, Department of Pharmaceutics and Analytical Chemistry, University of Copenhagen |
| 11:35 - 11:55 | Towards dendrimer-based antibiotics Stud. scient. Jon S. Hansen, Department of Chemistry, University of Copenhagen |
| 12:05 - 12:50 | Discussion |
| 12:50 - 13:00 | Closing remarks |
Aim and Background:
This symposium aims to give an overview of the biomedical use of dendrimers and how to develop and characterize the drug-dendrimer delivery systems. Using dendrimers for biomedical applications combines advanced polymer science with nanotechnology; in order to develop nanomedicine. Due to the possibilities of controlling and varying the components of these constructs, the dendrimer approach holds great promise for development of delivery vehicles for e.g nucleic acid drugs, such as siRNA, and protein drugs. However, development of safe and efficient dendrimer-based vehicles also address several questions such as how to characterize the delivery vehicles structurally, how to optimize the targeting effect by e.g. conjugating ligands, how to minimize potential side-effects etc. The speakers are members of leading groups performing dendrimer-research related to drug delivery and will thus provide the attendants with high-level input in the field. On the other hand, the meeting will not only be interesting for researchers synthesizing and using dendrimers, since some of the techniques and approaches, which will be presented are general for the field of nanomedicine.
Organized on behalf of the Drug Research Academy, FARMA by Hanne Mørck Nielsen, Department of Pharmacy and Analytical Chemistry at The Faculty of Pharmaceutical Sciences, University of Copenhagen, e-mail: hmn(at)farma.ku.dk
The participation is free of charge and is open for attendance by all interested parties. Number of attendants is limited to 100. registration to Lisbeth Ougaard at lou(at)farma.ku.dk no later than March 5th 2008.
