The Research Section Clinical Pharmacy conducts research within the areas:
The research in the group is focused on optimising the individual treatment of patients with medicine. To optimise dosing the group is using population pharmacokinetics. In the future the group will focus on the implementation of pharmacodiagnostic tests to optimise dosing and prevent serious adverse reactions in specific patient groups. The research include all patients categories with speciel emphasis on CNS diseases and patients treated with immunsuppressant drugs e.g. cancer patients, transplant patients, patients with chronic infections. Other focus areas are treatment of pain, fatigue and emesis.
The research in the immunopharmacology group is focused on the inflammatory potential of microorganisms and toxins. Activation of the innate immune system has a key role in inflammation including activation of phagocytes and release of proinflammatory cytokines and acute phase-reactants. The group has developed several in-vitro models of inflammation to study these markers of an activated immune system. Inflammation is interesting in different context ranged from in-vitro pyrogen test of medicine, measurement of inflammatory compounds in indoor air and role of low grade inflammation in the pathogenesis of inflammatory diseases like type 2 diabetes and atherosclerosis.
The group has expertise in measuring inflammatory compounds in the picogram range in medicine and simple matrix. To study low grade inflammation it is necessary to measure inflammatory mediators in the picogram range in body fluids like blood and serum. It is our goal to develop methods which can fulfill this.
To further develop the clinical aspect of inflammation cooperation with partners in academia and industry are established.
Clinical pharmacy, optimising drug therapy, pharmacokinetics and microbiological testing of medicine are unic target teaching areas for pharmacy students. Excellence in teaching within these areas is achieved only by being founded on the highest level of research. The goal of the group is to achieve competance at the highest international level within clinical pharmacy, pharmacokinetics, and immunopharmacology. To achieve this goal research and teaching coorporation has been established with several partners in academia and the pharmaceutical industry nationally as well as internationally. Another prime goal for the group is to establish a outstanding excellent master degree in Clinical Pharmacy and Practice.
Betina Schøler
Janne Colding
Alex Boje
Mikka Frankel
Mikkel Krogh
Katarina Gesser
Bettina Nygaard Nielsen
Pernille Ravn
University of Copenhagen
Faculty of Pharmaceutical Sciences
Universitetsparken 2
2100 Copenhagen
Denmark
Phone +45 35 33 60 00
Fax +45 35 33 60 01
Mail farma@farma.ku.dk
Web www.farma.ku.dk