Mini-symposium: Drug discovery & development – in an IT perspective

Wednesday, September 8, 2010 at 13:00-17:00 in the Benzon Auditorium

The Faculty of Pharmaceutical Sciences, Universitetsparken 2, 2100 Copenhagen

Information Technology plays a steadily increasing role in the discovery and development of new drugs. The DRA minisymposium “Drug Discovery & Development – in an IT-Perspective” will focus on the applications and importance of IT in different stages of the process. Experts within systems biology, drug discovery informatics, quantitative pharmacology and the clinical development process – together covering most of the discovery and development workflow - will all give their view on the role of IT within their particular area of expertise.

To close the day, Guy M. Lefever, IBM Global Business Services, Life Sciences/Pharma, will gaze into the crystal ball and give his opinion on the role of IT in drug discovery and development 10 years from now.

The symposium is arranged on behalf of the Drug Research Academy (DRA) by Thomas Balle, KU/PHARMA and Claus S. Kallesøe, H. Lundbeck A/S. Participation is free of charge and registration is not required. For further information please contact tb(at)farma.ku.dk.

Click here to find the programme in pdf format.

Thomas Skøt Jensen, Assoc. Prof., Center for Biological Sequence Analysis, Technical University of Denmark
Systems Biology in Drug Discovery

In recent years, biological data have been generated with an ever increasing pace accentuating the need for proper storing and organizing of data. With the increase in data Systems Biology, where focus is on the system rather than the individual component, has emerged. In this talk, I will present a Systems Biology study based on the observation that diseases with overlapping phenotypes often share molecular level mechanisms. In the study heterogeneous data is analyzed and integrated to identify disease-related genes relevant for drug discovery

Claus S. Kallesøe, Head of Drug Discovery Informatics, H. Lundbeck A/S
The Role of IT in R&D

No abstract.

Christoffer Wenzel Tornøe, Head of Quantitative Clinical Pharmacology, Novo Nordisk A/S
IT Challenges in Model-Based Drug Development

Model-based drug development allows for integration of data from different studies in a logical manner based on the understanding of the drug, disease, and trial characteristics. A requirement for model-based drug development is the creation of IT tools with 1) standards for raw and analysis data in order to build databases, 2) model and script libraries, and 3) queryable repositories of results and reports. This enables efficient and timely use of the totality of information to be used in the design of the next clinical trial.

Rasmus Nelund, Project Director, Herax
IT in Clinical Development - When Science, IT and Processes Meets

As technology, processes and data standards continue to evolve and integrate within biopharmaceuticals and healthcare, keeping pace with future trends is essential in improving the efficiency and speed of clinical research and in getting innovative medicines to patients. The presentation will focus on the landscape of applications in clinical development from Clinical Trial Management Systems via Electronic Data Capture to Clinical Data Warehouse and further on to submission. It will give an overview of how the clinical development applications are linked to the processes of developing medicine.

Guy M. Lefever, Partner, IBM Global Business Service, Life Sciences/Pharma
Pharma IT 2020 : Connecting the Dots

Integration of Life Sciences and Healthcare information will become the major playing field for better understanding the efficacy of existing drugs and translating this know how into the discovery and development of new drugs.  Information silo's within companies and between different stakeholders within the healthcare ecosystem will have to be broken down in order to allow our science to make a fundamental step forward.

We will review historical assumptions (Pharma2010) and define the key steps needed to achieve fundamental breakthroughs in our ways of working and the way he have built and operated our systems.