Drug-oriented analytical chemistry
Drug-oriented analytical chemistry comprises the Faculty’s research within three main fields:
- Basic studies of separation mechanisms in separation sciences
- Drug metabolism and bioanalysis
- Metabonomics and diagnostics.
The basic research in separation sciences bring forward new principles and techniques to be used in research related to low-molecular weight compounds present in complex biological samples of animal, plant and microbial origin. Included are studies of low to medium molecular weight metabolites, clarification of their origin, identity, function and significance, and developing technology platforms for research.
Since the interest in modern life sciences shifts from traditional reductive approaches to integrative approaches, emphasis is increasingly placed on comprehensive studies of arrays of metabolites, or of the whole metabolic complement of an organism – the metabonome.
Metabonomics addresses the question of multiparameter metabolic responses to various changes, including disease or treatment of a patient with a drug. There is growing recognition that metabonome research/metabonomics is a necessary supplement to genome research/genomics and proteome research/proteomics.
