Specialer
Pharmaceutical formulation/Biomacromolecules
The research focus is on development of optimal drug delivery systems intended for delivery of therapeutic biomacromolecules, such as peptides, proteins and siRNA. This type of drugs represents an increasing part of new drugs under development and in clinical trials.
The aim of our research is to gain a detailed understanding of the challenges associated with design drug delivery systems for a obtaining optimal and targeted delivery of biomacromolecules both by injection and by non-injectable routes of administration (e.g. oral, pulmonal, cutaneous).
We thus focus our research around different types of formulations including stabilized solutions, polymer or lipid based particulate drug delivery systems. These drug delivery systems are closely investigated and optimized with regard to the effect on e.g. the stability of these drugs (e.g conformational changes and irreversible aggregation of proteins) and the effect on targeting and controlled release of the drug in pharmaceutically relevant media or upon application to in vitro or in vivo models.
We collaborate with researchers in the industry and at universities both in DK and abroad
hjemmeside:
Biomakromolekyler
Specialevejledere
Alle vejledere sidder i bygning 13
Camilla Foged
Lektor
E-mail: cfo(at)farma.ku.dk
Telefon: 35 33 64 02
Rum: 411
siRNA/oligo nucleotide formulation, particulate drug delivery systems, vaccine formulation, cell penetrating peptides, nanoparticles, targeting
Vaccine formulation and adjuvant research
Hanne Mørck Nielsen
Lektor
E-mail: hmn(at)farma.ku.dk
Telefon: 35 33 63 46
Rum: 425
Drug delivery systems for biomacromolecules (peptides), peptide carriers, cell penetrating peptides, nano/microparticles, targeting, interaction with, uptake and transport in cells, mucosal delivery
Specialer
Eva Horn Møller
Lektor
E-mail: ehm(at)farma.ku.dk
Telefon: 35 33 65 29
Rum: 415b
Advanced drug delivery of peptides (proteins), chemical modification of peptides (proteins), development of formulations for peptides (proteins) for parenteral and oral delviery, stability and structure of peptides (proteins) in drug delivery systems
Lene Jørgensen
Lektor
E-mail: lej(at)farma.ku.dk
Telefon: 35 33 63 69
Rum: 418
Advanced drug delivery af peptides (proteins), drug delivery systems, lipid-based formulation, protein adsorption, interactions between excipients and proteins, emulsions
Marco van de Weert
Lektor
E-mail: mvdw(at)farma.ku.dk
Telefon: 35 33 61 86
Rum: 426a
Protein formulation, protein fibrillation/aggregation, freeze drying, protein-excipient interactions
