My main research interest is small molecules isolated from plants, fungi or other organisms. The focus of my work is primarily directed towards the isolation and identification process which has made me proficient in liquid chromatography, Mass spectrometry and nuclear magnetic resonance spectroscopy.

My PhD project primarily revolves around a hyphenated NMR technique, where HPLC-separated natural compounds are trapped and concentrated on solid phase extraction cartridges before being eluted into NMR tubes or NMR flowprobe (HPLC-SPE-NMR). 

Our lab is equipped with a 600MHz Bruker Avance NMR spectrometer with a 1.7mm cryoprobe and samplejet - this setup combined with the highly automated HPLC-SPE system provides us with a high capacity and throughput.

This high throughput setup generates an excessive amount of data which needs to be sorted to ensure that valuable spectrometrist time is spend on unknown compounds - a process often referred to as 'dereplication'. The most common dereplication method used is Mass Spectrometry as a high resolution MS can provide the spectrometrist with a molecular formula which can easily be searched through a database. MS as a dereplication tool has proven its worth on several occasions, but as a NMR geek I cannot but think that the structural information provided by even a simple ¹H NMR spectrum are more suitable for unambigously identifying known compounds.
Therefore, I am currently working on developing a matlab-based natural products NMR database to be used as a dereplication tool.

August 2009 - present:
PhD fellow, Department of Molecular Drug Research, Faculty of Pharmaceutical Sciences, University of Copenhagen.

May 2008 - August 2009
Research Scientist at MycoTeQ A/S

September 2002 - May 2008
M.Sc. Chemical Engineering, Institute for System Biology, Technical University of Denmark

September 2007-January 2008
M.Sc. thesis work at Institute for Molecular Bioscience, University of Queensland, Australia

Drug Research Academy equipment grant - 50.000 DKK

Reviewer on Planta Medica and South African Journal of Botany

Supervisor on 3 M.Sc. Projects

Co-organizer of TOKS XII (Meeting for organic chemistry students)