Kristine Andersen Krogh

Scientific Career

Research group leader of the Section of Toxicology, 2010
Associate Professor at The Department of Pharmaceutics and Analytical Chemistry, The Faculty of Pharmaceutical Sciences, University of Copenhagen, 2009
Assistant Professor at The Department of Pharmaceutics and Analytical Chemistry, The Faculty of Pharmaceutical Sciences, University of Copenhagen, 2003
Ph.D. from the Danish University of Pharmaceutical Sciences, 2003
University Instructor at the Department of Analytical Chemistry, The Danish University of Pharmaceutical Sciences, 2002
Research Assistant at NERI, Department of Environmental Chemistry, 2001
Guest Researcher at Consell Superior d’Investigacions Científiques (CSIC), Departament de Quimica Ambiental (IIQAB), in Barcelona, Spain, 2000
PhD. student at NERI, Department of Environmental Chemistry and Department of Atmospheric Environment, 1999
PhD. student enrolled at the Royal Danish School of Pharmacy, Department of Analytical and Pharmaceutical Chemistry, 1999
Academic staff at the National Environmental Research Institute (NERI), Department of Lake and Estuarine Ecology, 1998
Master in Science in Chemistry and Biotechnology at Århus University

Research Interests

Environmental analytical chemistry of biological complex samples using:

• sample preparation: solid phase extraction (SPE), hollow fibre supported liquid membrane extraction (HF-SLM) and pressurised liquid extraction (PLE) 
• separation techniques: HPLC-UV, LC-MS, LC-MS-MS and HPLC-radiodetection to quantify 3H and 14C labelled compounds.

Occurrence and fate of pharmaceuticals and endocrine disrupting compounds in terrestrial and aqueous environments.
Special focus on fate processes such as sorption and transformation (hydrolysis, photolysis and biodegradation).
Effect-directed analysis to identification of hazardous environmental transformation products from pharmaceuticals (in particular antibiotics and antiparasitics).

Research Projects

Participating in the following research projects: 

• CREAM - CenteR for Environmental and Agricultural Microbiology. Project financed by the Villum Kann Rasmussen Foundation. Project in collaboration with UC-LIFE, UC-SCIENCE, GEUS and DTU (2011-2014). http://www.cream.life.ku.dk/
• CREAM - CenteR for Environmental and Agricultural Microbiology. Project financed by the Villum Kann Rasmussen Foundation. Project in collaboration with UC-LIFE, GEUS and DTU (2006-2011). http://www.cream.life.ku.dk/ 
• ERApharm - Environmental Risk Assessment of Pharmaceuticals. ERAPharm is funded within the priority 'Global change and ecosystems' of the 6th framework programme of the European Commission (project no SSPI-CT-2003-511135). Project in collaboration with 13 different research institutions and pharmaceutical industry within Europe (2004-2007). http://www.erapharm.org/ 
• Development of analytical methods to determine antiparasitic veterinary pharmaceuticals in soil. Research stay abroad financed by The Governmental Agricultural- and Veterinary scientific Research Board (SJVF) within the Research Agency. Guest Researcher at the Federal Institute of Hydrology in Koblenz, Germany (2004).
• Survey of estrogenic activity in the Danish Aquatic Environment. Project financed by the Danish Environmental Protection Agency. Project in collaboration with Cowi, SDU and Eurofins (2003-2005).
• SOUND - Molecular Tools for Sustainable Land Use. Project financed by the Statens Jordbrugs- og Veterinærvidenskabelige Forskningsråd. Project in collaboration with KVL, GEUS, DMU, DJF (2003–2005).

Supervision

Theses

Publications

Publications 2007 - present
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2006 - 2001
Stuer-Lauridsen, F., Kjølholt, J., Høibye, L., Hinge-Christensen, S., Ingerslev, F., Hansen, M., Krogh, K. A., Andersen, H. R., Halling-Sørensen, B., Bjerregaard, P., Frost, B., Hansen, N., and Køppen, B.
Survey of estrogenic activity in the Danish Aquatic Environment.
Environmental Project. MST, 2005
Krogh, K.A.; Halling-Sørensen B.; Mogensen, B.B.; Vejrup, K.V.
The Environmental Impact of Surfactant Ingredients in Pesticide Formulations - Special Focus on Alcohol Ethoxylates and Alkylamine Ethoxylates.
In: Zoller U, ed. Handbook of Detergents, Part B: Environmental Impact. New York: Marcel Dekker, pp. 691-717, 2004
Ingerslev, F., Andersen, H. R., Jakobsen, A. M., Krogh, K. A., Søeborg, T., Hansen, M. og Halling-Sørensen, B.
Nye kemiske analysemetoder finder østrogener i ng/l niveau.
Lægemiddelforskning 2003. (http://www.dfh.dk/publikationer/laegemiddelforskning/laegemiddelforsk_03.pdf)
Ingerslev, F., Andersen, H., Hansen, M., Jacobsen, A.M., Krogh, K.A., Søeborg, T. Halling-Sørensen, B.
En præliminær kortlægning af steroidøstrogen-udledningen fra danske rensningsanlæg.
Dansk Kemi, 84 nr. 5, pp. 38-39, 2003
Krogh, K.A.; Mogensen, B.B.; Halling-Sørensen B.; Cortés, A.; Vejrup, K.V. and Barceló, D.
Analysis of alcohol ethoxylates and alkylamine ethoxylates in soil using pressurised liquid extraction and liquid chromatography-mass spectrometry.
Analytical and Bioanalytical Chemistry 376, 7, pp. 1089-1097, 2003
Krogh, K.A.; Halling-Sørensen B.; Mogensen, B.B. and Vejrup, K.V. Environmental properties and effects of nonionic surfactant adjuvants in pesticides: a review.
Chemosphere 50, 871-901, 2003
Andersen, H. R., Jacobsen, A. M., Krogh, K. A., Ingerslev, F. og Halling-Sørensen, B.
Hormoner fra mennesket forstyrrer reproduktionen hos fisk. Lægemiddelforskning 2002. (www.dfh.dk/publikationer/laegemiddelforskning/laegemiddelforsk_02.pdf)
Krogh, K.A.; Vejrup, K.V.; Mogensen, B.B. and Halling-Sørensen B.
Liquid chromatography-mass spectrometry method to determine alcohol ethoxylates and alkylamine ethoxylates in soil interstitial water, groundwater and surface water.
Journal of Chromatography A 957, 1, p. 45-57, 2002
Krogh, K.A.; Vejrup, K.V.; Mogensen, B.B. and Halling-Sørensen, B.
Adjuvants in pesticides in the aquatic environment.
Proceedings from the 6th International Symposium for Agrochemicals ISAA 2001, p.164-169.