Molecular Pharmacology Research
The aim of our research is to study the function of receptors and transporters at the molecular level, and to develop novel subtype-selective compounds. Increasingly, we are also studying the function of selected ligands and targets ex vivo and in vivo using animal models and genetically modified mice.
Most of our projects are interdisciplinary using computer modeling and medicinal chemistry in conjunction with molecular pharmacology. Thus we use modeling of 3D structures to predict receptor/transporter interactions and to design selective ligands for chemical synthesis. For pharmacological assessment and delineation of the physiological function of the receptor/transporter in question, we use both our developed efficient pharmacological assays and phenotyping of genetically modified mice.
The projects build on collaborations with the Medicinal Chemistry, Chemical Biology and Structural Biology groups at the department as well as many external academic and pharmaceutical industry collaborators in Denmark and abroad.
Group Members
Professor
Hans Bräuner-Osborne
Associate professors
David Gloriam [Modeling]
Anders A. Jensen
Daniel Sejer Pedersen [MedChem]
Petrine Wellendorph
Postdocs
Bjarke Abrahamsen
Kirsten Høstgaard-Jensen
Jesper Mosolff Mathiesen
Sanela Smajilovic
PhD students
Kirsten Bayer Andersen
Tina Bay
Anne Bjørnskov Jensen
Christoffer Clemmensen
Laura Friis Eghorn
Harriet Hammer
Vignir Isberg [Modeling]
Henrik Johansson [MedChem]
Trine Kvist
Morten Grupe Larsen
Christina Mølck
Lenea Nørskov-Lauritsen
Jonas Skovgaard-Petersen
Alex Rojas Bie Thomsen
Sarah Maria Trattnig
Line Vedel
Inge Stengaard Villumsen
Research assistants
Diala Awad
Anette Østergaard Linde
Master thesis students
Agnes Gasiorek
Trine Cecilia Gregersen
Medina Hotilovac
Stine Jacobsen
Annie Jespersen
Scholar student
Mette Westergaard-Andersen
Alumni
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Recent news
23-01-12 New grants
David Gloriam and Hans Bräuner-Osborne have each received 200,000 DKK from the Lead Discovery initiative at the Department of Molecular Drug Research.
19-12-12 New grants
Petrine Wellendorph, Anders A. Jensen and Hans Bräuner-Osborne have received grants of 50,000 DKK, 45,000 DKK and 40,000 DKK from The A. P. Møller Foundation for the Advancement of Medical Sciences.
7-12-12 New grants
Sanela Smajilovic and Jesper Mosolff Mathiesen have each received a 2-year post doc grant from the Carlsberg Foundation.
