DRA Lecture: Mutagenesis Mediated Pharmacological Inter-conversion of Amino Acid-Activated Receptors
<typohead type=4 align=left>Friday, August 6th, 2004 at 11:00 to 12:00 in Auditorium 3</typohead>
The Danish University of Pharmaceutical Sciences Universitetsparken 2, 2100 Copenhagen O
Professor David R. Hampson
University of Toronto, Canada
Abstract
David R. Hampson har i det seneste årti fokuseret på metabotrope glutamat receptorer, hvor han bl.a. har undersøgt glutamats bindingssted vha. mutagenese.
Seneste artikler:
Yao Y, Koo JC, Wells JW, Hampson DR. Expression of a truncated secreted form of the mGluR3 subtype of metabotropic glutamate receptor. Biochem. Biophys. Res. Commun. (2004) 319:622-628.
Kuang D, Yao Y, Wang M, Pattabiraman N, Kotra LP, Hampson DR. Molecular similarities in the ligand binding pockets of an odorant receptor and the metabotropic glutamate receptors. J. Biol. Chem. (2003) 278: 42551-42559.
Yao Y, Pattabiraman N, Michne WF, Huang XP, Hampson DR. Molecular modeling and mutagenesis of the ligand-binding pocket of the mGlu3 subtype of metabotropic glutamate receptor. J. Neurochem. (2003) 86: 947-957.
Rosemond E, Peltekova V, Naples M, Thogersen H, Hampson DR. Molecular determinants of high affinity binding to group III metabotropic glutamate receptors. J. Biol. Chem. (2002) 277: 7333-7340.
The lecture is organised by: Hans Bräuner-Osborne (the Danish University of Pharmaceutical Sciences) and is open for attendance by all interested parties.
