News
May 16, 2012
Group member Jesper M. Mathiesen co-authors a landmark article in todays issue of Nature together with the Brian Kobilka group at Stanford University, USA. In the article, the X-ray 3D structure of the µ-opioid receptor is revealed, which is an important drug target. Interestingly, it is also demonstrated that the receptor is a dimer in the crystal, which correlate with previous pharmacological and biochemical data.
February 9, 2012
Hans Bräuner-Osborne received the Elite Researcher Prize of 1.2 million DKK from the Danish Ministry of Research, Innovation and Higher Education. The prize is given to an outstanding Danish researcher for an excellent contribution to Danish science.
January 23, 2012
David Gloriam and Hans Bräuner-Osborne have each received 200,000 DKK from the Lead Discovery initiative at the Department of Molecular Drug Research to purchase privileged structure and endogenous peptide libraries for our GPCR deorphanization projects.
December 19, 2011
Petrine Wellendorph, Anders A. Jensen and Hans Bräuner-Osborne have received grants of 50,000 DKK, 45,000 DKK and 40,000 DKK from The A. P. Møller Foundation for the Advancement of Medical Sciences for the projects "Identification of compounds with specific action on GABA transporters in the brain", "Development of glutamate transporter ligands and use of these in studies of transporter physiology" and "Development of novel selective serotonin 5-HT2A receptor ligands", respectively.
December 7, 2011
Sanela Smajilovic and Jesper Mosolff Mathiesen have each received a 2-year post doc grant from the Carlsberg Foundation. Furthermore, Petrine Wellendorph got a grant to hire Anders Bue Klein as post doc for 1 year.
December 1, 2011
Anders A. Jensen received the annual Researcher of the Year prize of 20,000 DKK from the Faculty of Pharmaceutical Sciences. The prize was given based on his high level research within molecular pharmacology and medicinal chemistry.
November 23, 2011
David Gloriam has received a grant of 300,000 DKK from the Novo Nordisk Foundation for a project entitled "Chemogenomic Identification Of Pharmacological Tool Compounds for Orphan Receptors".
October 10, 2011
Hans Bräuner-Osborne has received a grant of 60,000 DKK from Brødrene Hartmanns Fond to cover running costs for the project entitled "Characterization of binding mechanisms for mGluR5 selective allosteric modulators".
September 29, 2011
In todays issue 477 of Nature group member Jesper M. Mathiesen co-authors landmark article entitled "Crystal structure of the ß2 adrenergic receptor–Gs protein complex". During his post doc Jesper M. Mathiesen has been visiting scientist for 1 year in the professor Brian K. Kobilka group at Stanford where he performed experiments published in the article, which for the first time shows the 3D structure of a G protein-coupled receptor and its G protein.
September 2, 2011
David Gloriam has received a grant of 200,000 SEK from Stiftelsen Olle Engkvist Byggmästare to purchase a library of privileged structures for the project entitled "Chemogenomic identification of pharmacological tool compounds for orphan receptors".
September 1, 2011
Hans Bräuner-Osborne has received a grant of 500,000 DKK from Novo Nordisk Foundation to cover post doc salary and running costs for the project entitled "Delineation of the molecular mechanism(s) of metabolic disturbances in GPRC6A knockout mice".
April 13, 2011
Anders A. Jensen has received a grant of 1,100,000 DKK from the Lundbeck Foundation to hire a PhD student for a project entitled "Human alpha6 nicotinic acetylcholine receptors: Molecular pharmacology and therapeutic perspectives".
March 25, 2011
Anders A. Jensen has received a highly prestigeous Hallas Møller stipend from the Novo Nordisk Foundation of 11 million DKK for a 5-year period to study GABAA receptors using molecular pharmacological and genetic tools.
February 7, 2011
Anders A. Jensen has received a grant of 100,000 DKK from Aase og Ejner Danielsens Fond to cover running costs for the project entitled "Development and characterization of alpha6 nicotininc acetyl choline receptor ligands and evaluation of their therapeutic potential as anti-parkinsons disease drugs".
December 21, 2010
Hans Bräuner-Osborne has received a grant of 50,000 DKK from The A. P. Møller Foundation for the Advancement of Medical Sciences for the project "Characterization of binding mechanisms for mGluR5 selective allosteric modulators".
December 17, 2010
Vikram Kjøller Bhatia has received the prestigenous Ung Eliteforsker [Young Elite Researcher] prize of approximately 1 million DKK from The Danish Council for Independent Research. The prize will give a great boost to his post doc project entitled "Molecular and cellular pharmacology of the GPRC6A G protein coupled receptor".
December 13, 2010
David E. Gloriam has received a 3-year post doc grant of approximately 1,2 million DKK from the Carlsberg Foundation and 1 million DKK from the Lundbeck Foundation for a project entitled "Chemogenomic identification of pharmacological tool compounds for orphan receptors".
December 6, 2010
Anders A. Jensen has received a grant of 200,000 DKK from the Novo Nordisk Foundation for a project entitled "Molecular pharmacology of human alpha6 nicotinic acethylcholine receptors".
September 30, 2010
Hans Bräuner-Osborne has received a grant of 1,525,000 DKK from the Lundbeck Foundation to hire a PhD student for a project entitled "Elucidation of the physiological ligand and function of GPR139 - a G protein-coupled receptor linked to neurological disease".
July 5, 2010.
Kirsten Bayer Andersen and Morten Grupe have each received an Industrial PhD scholarship to work on collaborative projects between H. Lundbeck A/S and Hans Bräuner-Osborne, and NeuroSearch A/S and Anders A. Jensen, respectively.
July 1, 2010.
Our group has moved to Symbion Science Park located 2 km from the Department of Medicinal Chemistry building. We have thereby obtained much needed additional laboratory and office space in a state-of-the-art facility.
June 11, 2010.
Bjarke Abrahamsen and Vikram Kjøller Bhatia have each received 3-year post doc grants of approximately 3 million DKK from the Danish Medical Research Council to work on the molecular pharmacology of EAAT glutamate transporters and the GPRC6A receptor, respectively.
March 19, 2010.
Anders Asbjørn Jensen has received a grant of 250,000 DKK from The Augustinus Foundation for running costs for the project "Molecular pharmacology studies of excitatory amino acid transporters and their ligands".
February 9, 2010
Hans Bräuner-Osborne has received a grant of 122,000 DKK from the Danish Medical Research Council to hire Master of Pharmacy student Semsi Kiiic as scholarship student for a project entitled "Development of the first selective ligands for the GPRC6A receptor - a novel human G protein-coupled receptor with unknown physiological functions".
December 22, 2009
Hans Bräuner-Osborne has received a grant of 148,000 DKK from The Augustinus Foundation to obtain a setup to perform electrophysiological recordings in Xenopus oocytes expressing NMDA receptors.
December 21, 2009
Hans Bräuner-Osborne has received a grant of 3,120,000 DKK from the Danish Medical Research Council to hire a post doc for a project entitled "Development of allosteric ß2 adrenergic receptor modulators and delineation of their mechanism of action".
December 14, 2009.
Today Anders A. Jensen received a grant of 300.000 DKK from the Carlsberg Foundation to acquire a FLEXstation3 Plate Reader.
September 30, 2009
Hans Bräuner-Osborne has received a grant of 1,200,000 DKK from the Lundbeck Foundation to hire a PhD student for a project entitled "Identification of allosteric modulators from extended ß2 adrenergic receptor agonist fragments".
September 22, 2009
Hans Bräuner-Osborne has received a grant of 50,000 DKK from the Beckett Foundation to cover running costs for the project entitled "Regulation of phosphate homeostasis by the calcium-sensing receptor"
January 29, 2009
Today Trine Kvist will receive a "EliteForsk" travel prize of 250.000 DKK from the Ministry of Science Technology and Innovation. The prize will be used to travels to our collaborator professor Stephen F. Traynelis at Emory University, USA in order to study NMDA receptors by sophisticated electrophysiological methods.
December 22, 2008
Anders A. Jensen has received a grant of 1,700,000 DKK from the Lundbeck Foundation to hire a PhD student for a project entitled "Molecular pharmacology studies of the 5-HT3 serotonin receptor and other Cys-loop receptors".
December 17, 2008
Today it was announced that the Minstry of Science, Technology and Innovation has awarded 120 million DKK to establish the research center "Food, Fitness & Pharma for Health and Disease" at the University of Copenhagen. Our group participate in the center, which will be led by professor Thue W. Schwartz at the Faculty of Health.
December 14, 2008
Petrine Wellendorph has received a grant of 78,000 DKK from Fonden til Lægevidenskabens Fremme for the project "Cloning and characterization of the GHB receptor". The foundation is part of the A.P. Møller Foundation.
December 10, 2008
Today Anders A. Jensen received a grant of 450.000 DKK from the Carlsberg Foundation to acquire a medium throughput electrophysiological screening system and expand our diverse compound screening library.
December 5, 2008
Today we published a popular scientific article in Danish about our GABA transporter project in the annual magazine Lægemiddelforskning. Download the article here.
November 27, 2008
Anders A. Jensen and Hans Bräuner-Osborne have each received a grant of 250,000 DKK from the Novo Nordisk Foundation for the glutamate transporter and GPRC6A receptor projects, respectively.
November 26, 2008
Anders A. Jensen has received a grant of 1,620,000 DKK from the Danish Medical Research Council for the project "Molecular pharmacology studies of nicotinic cetylcholine receptors and GABA receptors".
November 21, 2008
Today Anders A. Jensen received 90,000 DKK from Aase og Ejner Danielsens Fond to expand our diverse screening compound library from 3,000 to 5,000 compounds.
November 4, 2008
Today the union PharmaDanmark published a informercial in the newspaper "Politiken" where ph.d. student Trine Kvist was pictured on the front page and professor Hans Bräuner-Osborne was interviewed about personalized medicine (on page 4). Download the informerical in PDF format here.
September 10, 2008
Today it was announced that Petrine Wellendorph has been awarded a prestigious For Women in Natual Sciences grant of 100,000 DKK sponsored by L'Oréal, UNESCO and The Royal Danish Academy of Science and Letters.
August 16, 2008
Jesper M. Mathiesen has received a grant of 122,000 DKK from the Lundbeck Foundation to cover running costs for the project entitled "Using the ß2 adrenoceptor to understand molecular mechanisms of allosteric modulation of GPCRs".
June 16, 2008
Hans Bräuner-Osborne has received a Alfred Benzon Investigator Fellowship to hire David Gloriam for the project entitled "Identification and elucidation of mechanism-of-action of allosteric ligands for the ß2-adrenergic receptor". Petrine Wellendorph has received a 1-year Alfred Benzon Researcher Stipend for the project entitled "Cloning and characterization of the GHB receptor".
June 15, 2008
Anders A. Jensen has received a grant of 97,000 DKK from Direktør Ib Henriksens Foundation and a grant of 70,000 DKK from The Augustinus Foundation to obtain a setup to perform electrophysiological recordings in Xenopus oocytes expressing ligand-gated ion-channels.
May 15, 2008
Jesper M. Mathiesen has received a 3-year post doc grant from the Danish Medical Research Council for the project entitled "Using the ß2 adrenoceptor to understand molecular mechanisms of allosteric modulation of GPCRs". The project is a collaborative effort with professor Brian Kobilka, Standford University, USA.
May 6, 2008
Hans Bräuner-Osborne has received a grant of 175,000 DKK from Simon Foughner Hartmanns Familiefond to cover equipment and running costs for the project entitled "The physiological function of the GPRC6A receptor".
April 16, 2008
Anders A. Jensen has received a grant of 50,000 DKK from Brødrene Hartmanns Fond to cover running costs for the project entitled "Studies of the mechanism-of-action of a novel type of cognitive enhancer".
April 7, 2007
Anders A. Jensen has received a grant of 80,000 DKK from Aase og Ejner Danielsens Fond to cover running costs for the project entitled "Studies of the mechanism-of-action of a novel type of cognitive enhancer".
December 28, 2007
Kasper Bø Hansen has received a grant of 50,000 DKK from Fonden af 17-12-1981 to cover running costs and equipment for the project entitled "Development and characterization of novel NMDA receptor ligands".
December 21, 2007
Hans Bräuner-Osborne has received a grant of 233,000 DKK from the Carlsberg Foundation. Together with a previous grant from the Augustinus Foundation and a research prize from the Torkil Holms Foundation the new grant will allow our group to obtain a sophisticated state-of-the electrophysiological set-up which will be able to e.g. measure currents through single ion-channels.
December 19, 2007
Hans Bräuner-Osborne has received a grant of 750,000 DKK from the Villum Kann Rasmussen Foundation to hire a postdoctoral fellow in medicinal chemistry on the GPRC6A receptor project.
December 19, 2007
Kasper Bø Hansen, Anders A. Jensen and Hans Bräuner-Osborne have each received a grant from the Danish Medical Research Council. KBH received a grant of 92,000 DKK to cover travel expenses for his research stay at Emory University whereas AAJ and HBO each received a grant of 81,000 DKK to hire two pharmaceutical master degree students as scholarship students in spring 2008.
December 17, 2007
Hans Bräuner-Osborne has received two grants from the Drug Research Academy: a 3-year ph.d. stipend co-financed by LEO Pharma and a 2-year post doc stipend co-financed by the Danish Medical Research Council. Keep an eye on the "Open positions" webpage where the positions will be posted in 2008.
December 13, 2007
We have just published a popular scientific article in Danish in the faculty publication Lægemiddelforskning. The article explains our data and possible implications in depression that was accepted for publication in Proc. Natl. Acad. Sci. USA two weeks ago. This is your chance to get an explanation of the results in layman's language. Download the article in PDF format here or download the whole issue of Lægemiddelforskning here.
December 10, 2007
Bolette Christiansen has received a grant of 50,000 DKK from Fonden til Lægevidenskabens Fremme for the project "Molecular pharmacology of human GABA transporters". The foundation is part of the A.P. Møller Foundation.
December 3, 2007
Hans Bräuner-Osborne has received a grant of 110,000 DKK from the Novo Nordisk Foundation for the project "Identification and characterization of novel selective NMDA receptor ligands".
November 28, 2007
Our manuscript entitled "A high frequency HTR3B variant associated with major depression dramatically augments the signaling of the human 5-HT3AB receptor" has just been accepted for publication in the prestigious high-impact journal Proc. Natl. Acad. Sci. USA. The study has been a collaborative effort between Karen Krzywkowski, Hans Bräuner-Osborne and Anders A. Jensen from our group and Paul A. Davies and Paula L. Feinberg-Zadek from the Massachusetts General Hospital, Boston, USA.
[link to journal]
November 27, 2007
Hans Bräuner-Osborne has received a grant of 1,440,000 DKK from the Danish Medical Research Council for the project "Characterization of GPRC6A – a promiscuous L-α-amino acid 7TM receptor with preference for basic amino acids".
November 9, 2007
Our department has just been granted a Programme of Excellence worth 24.5 million DKK by the University of Copenhagen. The programme, which focus on structure and pharmacology of ionotropic glutamate receptor, will be led by Dr. Jette Sandhold Kastrup. Our group participate with a sub-project on molecular pharmacology of NMDA receptors and will receive 3,250,000 DKK to conduct the study. [read more]
October 23, 2007
Anders A. Jensen og Lennart Bunch have received a grant of 1,500,000 DKK from the Lundbeck Foundation to study glutamate transporters.
October 5, 2007
Anders A. Jensen has received a grant of 1,600,000 DKK from the Lundbeck Foundation to study molecular pharmacological aspects of GABAA receptors.
[read more]
