Nils T. Nyberg

NMR, NMR, NMR, chemometrics, metabonomics, natural products. The tools I use are high field NMR spectrometers (mostly Bruker instruments), chemometrics (a.k.a. statistics), programming, mathematics and graphical visualization of results (mostly MATLAB).

1996: Master of Science in chemistry, (Fil. Mag i kemi) from University of Linköping/Uppsala University, Sweden.

2002: Ph.D. in Organic Chemistry, Swedish University of Agricultural sciences (SLU), Department of Chemistry. Supervisor: Prof. Lennar Kenne.

1994-1996: Kabi Pharmacia, Pharmacia, Pharmacia & Upjohn: Dep.of Analytical Chemistry, Uppsala, Sweden

1996-2002: Post graduate student at the Department of Chemistry, Swedish University of Agricultural Sciences (SLU), Uppsala, Sweden

2003-2006: Post doctoral fellow, Department of Chemistry, Carlsberg Laboratory, Copenhagen, Denmark

March 2007-present: Post doc., Natural Products Chemistry, Department of Medicinal Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, Denmark

Wubshet, S.G., K.T. Johansen, N.T. Nyberg, and J.W. Jaroszewski, Direct ¹³C NMR Detection in HPLC Hyphenation Mode: Analysis of Ganoderma lucidum Terpenoids. Journal of Natural Products, 2012. Accepted for publication 11/4-2012. http://dx.doi.org/10.1021/np200915c. 

Yilmaz, A., N.T. Nyberg, and J.W. Jaroszewski, Metabolic Profiling Based on Two-Dimensional J-Resolved ¹H NMR Data and Parallel Factor Analysis. Analytical Chemistry, 2011. 83(21): p. 8278-8285.

Johansen, K.T., S.G. Wubshet, N.T. Nyberg, and J.W. Jaroszewski, From Retrospective Assessment to Prospective Decisions in Natural Product Isolation: HPLC-SPE-NMR Analysis of Carthamus oxyacantha Journal of Natural Products, 2011. 74: p. 2454-2461.

Ioset, K.N., N.T. Nyberg, D.D. Van, P. Malnoe, K. Hostettmann, A.N. Shikov, and J.W. Jaroszewski, Metabolic profiling of Rhodiola rosea rhizomes by ¹H NMR spectroscopy. Phytochemical Analysis, 2011. 22: p. 158-165.

Yilmaz, A., N.T. Nyberg, P. Molgaard, J. Asili, and J.W. Jaroszewski, ¹H NMR metabolic fingerprinting of saffron extracts. Metabolomics, 2010. 6: p. 511-517.

Rasmussen, P., N. Nyberg, J.W. Jaroszewski, R. Krogh-Madsen, N.H. Secher, and B. Quistorff, Brain nonoxidative carbohydrate consumption is not explained by export of an unknown carbon source: evaluation of the arterial and jugular venous metabolome. Journal of Cerebral Blood Flow & Metabolism, 2010. 30: p. 1240-1246.

Nyberg, N.T., M.O. Nielsen, and J.W. Jaroszewski, Metabolic trajectories based on ¹H NMR spectra of urines from sheep exposed to nutritional challenges during prenatal and early postnatal life. Metabolomics, 2010. 6: p. 489-496.

Lauridsen, M., A.D. Maher, H. Keun, J.C. Lindon, J.K. Nicholson, N.T. Nyberg, S.H. Hansen, C. Cornett, and J.W. Jaroszewski, Application of the FLIPSY Pulse Sequence for Increased Sensitivity in ¹H NMR-Based Metabolic Profiling Studies. Analytical Chemistry, 2008. 80(9): p. 3365-3371.

Skovsted, I.C., M.B. Kerrn, J. Sonne-Hansen, L.E. Sauer, A.K. Nielsen, H.B. Konradsen, B.O. Petersen, N.T. Nyberg, and J.O. Duus, Purification and structure characterization of the active component in the pneumococcal 22F polysaccharide capsule used for adsorption in pneumococcal enzyme-linked immunosorbent assays. Vaccine, 2007. 25(35): p. 6490-6500.

Reenberg, T., N. Nyberg, J.O. Duus, D.J.L.J. van, and M. Meldal, Specific recognition of disaccharides in water by an artificial bicyclic carbohydrate receptor. European Journal of Organic Chemistry, 2007. 30: p. 5003-5009.

Petersen, B.O., E. Vinogradov, W. Kay, P. Wuertz, N.T. Nyberg, J.O. Duus, and O.W. Sorensen, H2BC: a new technique for NMR analysis of complex carbohydrates. Carbohydrate Research, 2006. 341: p. 550-556.

Nyberg, N.T. and O.W. Soerensen, Multiplicity-edited broadband HMBC NMR spectra. Magnetic Resonance in Chemistry, 2006. 44(4): p. 451-454.

Nyberg, N.T., J.O. Duus, and O.W. Sorensen, Heteronuclear Two-Bond Correlation: Suppressing Heteronuclear Three-Bond or Higher NMR Correlations while Enhancing Two-Bond Correlations Even for Vanishing ²J_CH. Journal of American Chemical Society, 2005. 127(17): p. 6154-6155.

Nyberg, N.T., J.O. Duus, and O.W. Sorensen, Editing of H2BC NMR spectra. Magnetic Resonance in Chemistry, 2005. 43(12): p. 971-974.

Hambraeus, G. and N. Nyberg, Enzymatic Hydrogenation of trans-2-Nonenal in Barley. Journal of Agricultural and Food Chemistry, 2005. 53(22): p. 8714-8721.

Nyberg, N.T., H. Baumann, and L. Kenne, Solid-phase extraction NMR studies of chromatographic fractions of saponins from Quillaja saponaria. Analytical Chemistry, 2003. 75(2): p. 268-274.

Nyberg, N.T., H. Baumann, and L. Kenne, Application of solid-phase extraction coupled to an NMR flow-probe in the analysis of HPLC fractions. Magnetic Resonance in Chemistry, 2001. 39(5): p. 236-240.

Nyberg, N.T., L. Kenne, B. Ronnberg, and B.G. Sundquist, Separation and structural analysis of some saponins from Quillaja saponaria Molina. Carbohydrate Research, 2000. 323: p. 87-97.

Bergloef, T., N. Nyberg, A. Hellstroem, and H. Kylin, Off-line SFE-NMR analysis of DDT in soil samples. Organohalogen Compd., 1998. 35: p. 85-87.