Publications 2010


University of Copenhagen Research Database:
Find a researcher (Dansk: Find en forsker)
With DOI or full text documents.

Abdelgadir HA, Jäger AK, Johnson SD, van Staden J. Influence of plant growth regulators on flowering, fruiting, seed oil content, and oil quality of Jatropha curcas. S Afr J Bot. 2010, 76(3):440-446.

Agnolet S, Jaroszewski JW, Verpoorte R, Stærk D. 1H NMR-based metabolomics combined with HPLC-PDA-MS-SPE-NMR for investigation of standardized Ginkgo biloba preparations. Metabolomics. 2010, 6(2):292-302.

Andersen J, Olsen L, Hansen KB, Taboureau O, Jørgensen FS, Jørgensen AM, Bang-Andersen B, Egebjerg J, Strømgaard K, Kristensen AS. Mutational mapping and modeling of the binding site for (S)-citalopram in the human serotonin transporter. J Biol Chem. 2010, 285(3):2051-2063.

Andersen NH, Christensen NJ, Lassen PR, Freedman TB, Nafie LA, Strømgaard K, Hemmingsen LBS. Structure and absolute configuration of ginkgolide B characterized by IR- and VCD spectroscopy. Chirality. 2010, 22(2):217-223.  

Armishaw CJ, Singh N, Medina-Franco JL, Clark RJ, Scott KCM, Houghten RA, Jensen AA. A synthetic combinatorial strategy for developing α-conotoxin analogs as potent α7 nicotinic acetylcholine receptor antagonists. J Biol Chem. 2010, 285(3):1809-1821.

Bach A, Stuhr-Hansen N, Thorsen TS, Bork N, Moreira IS, Frydenvang K, Padrah S, Christensen SB, Madsen KL, Weinstein H, Gether U, Strømgaard K. Structure-activity relationships of a small-molecule inhibitor of the PDZ domain of PICK1. Org Biomol Chem. 2010, 8(19):4281-4288.

Berthold PR, Shiraishi T, Nielsen PE. Cellular delivery and antisense effects of peptide nucleic acid conjugated to polyethyleneimine via disulfide linkers. Bioconjug Chem. 2010, 21(10):1933-1938.

Bornholdt J, Felding J, Clausen RP, Kristensen JL. Ring opening of pymisyl-protected aziridines with organocuprates. Chem Eur J. 2010, 16(41):12474-12480.

Bornholdt J, Felding J, Kristensen JL. Synthesis of enantiopure 3-substituted morpholines. J Org Chem. 2010, 75(21):7454-7457.

Bourbeillon J, Orchard S, Benhar I, Borrebaeck C, de Daruvar A, Dübel S, Frank R, Gibson F, Gloriam DEI, Haslam N, Hiltker T, Humphrey-Smith I, Hust M, Juncker D, Koegl M, Konthur Z, Korn B, Krobitsch S, Muyldermans S, Nygren P, Palcy S, Polic B, Rodriguez H, Sawyer A, Schlapshy M, Snyder M, Stoevesandt O, Taussig MJ, Templin M, Uhlen M, van der Maarel S, Wingren C, Hermjakob H, Sherman D. Minimum information about a protein affinity reagent (MIAPAR). Nat Biotechnol. 2010, 28(7):650-653.

Cailly TBG, Begtrup M. Regioselective functionalization of 2-(2'-fluorophenyl)-3-cyanopyridine and its cyclization to benzo[h]-1,6-naphthyridines. Tetrahedron. 2010, 66(6):1299-1307.

Chi CN, Bach A, Gottschalk M, Kristensen AS, Strømgaard K, Jemth P. Deciphering the kinetic binding mechanism of dimeric ligands using a potent plasma-stable dimeric inhibitor of postsynaptic density protein-95 as an example. J Biol Chem. 2010, 285(36):28252-28260.

Christensen MK, Erichsen KD, Trojel-Hansen C, Tjørnelund J, Nielsen SJ, Frydenvang KA, Johansen TN, Nielsen B, Sehested M, Jensen PB, Ikaunieks M, Zaichenko A, Loza E, Kalvinsh I, Björkling F. Synthesis and antitumor effect in vitro and in vivo of substituted 1,3-dihydroindole-2-ones. J Med Chem. 2010, 53(19):7140-7145.

Conti P, Pinto A, Tamborini L, Madsen U, Nielsen B, Bräuner-Osborne H, Hansen KB, Landucci E, Pellegrini-Giampietro DE, De Sarro G, Donato Di Paola E, De Micheli C. Novel 3-carboxy- and 3-phosphonopyrazoline amino acids as potent and selective NMDA receptor antagonists: Design, synthesis, and pharmacological characterization. ChemMedChem. 2010, 5(9):1465-1475.

Diness F, Meldal MP. Amino acid derived 1,4-dialkyl substituted imidazolones. Biopolymers. 2010, 94(2):236-241.

Emami SA, Afsharypuor S, Asili J, Sairafianpour M. Chemical composition of the essential oils from Iranian conifers. Part I: Aroma profiles of leaves and fruits of Juniperus polycarpos var. polycarpos (Cupressaceae). JEOR. 2010, 22(2):103-106.

Erichsen MN, Huynh THV, Abrahamsen B, Bastlund JF, Bundgaard C, Monrad O, Bekker-Jensen A, Nielsen CW, Frydenvang KA, Jensen AA, Bunch L. Structure-activity relationship study of first selective inhibitor of excitatory amino acid transporter subtype 1: 2-amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (UCPH-101). J Med Chem. 2010, 53(19):7180–7191.

Ettrup A, Palner M, Gillings N, Santini MA, Hansen M, Kornum BR, Rasmussen LK, Någren K, Madsen J, Begtrup M, Knudsen GM. Radiosynthesis and evaluation of 11C-CIMBI-5 as a 5-HT2A receptor agonist radioligand for PET. J Nucl Med. 2010, 51(11):1763-1770.

Foderà V, van de Weert M, Vestergaard B. Large-scale polymorphism and auto-catalytic effect in insulin fibrillogenesis. Soft Matter. 2010, 6(18):4413-4419.

Frydenvang KA, Pickering DS, Greenwood JR, Krogsgaard-Larsen N, Brehm L, Nielsen B, Vogensen, SB, Hald, H, Kastrup, JS, Krogsgaard-Larsen, P, Clausen, RP. Biostructural and pharmacological studies of bicyclic analogues of the 3-isoxazolol glutamate receptor agonist ibotenic acid. J Med Chem. 2010, 53(23):8354-8361.

Frølund S, Bella A, Kristensen AS, Ziegler HL, Witt M, Olsen CA, Strømgaard K, Franzyk H, Jaroszewski JW. Assessment of structurally diverse philanthotoxin analogues for inhibitory activity on ionotropic glutamate receptor subtypes: Discovery of nanomolar, nonselective, and use-dependent antagonists. J Med Chem. 2010, 53(20):7441-7451.

Gloriam DEI, Orchard S, Bertinetti D, Björling E, Bongcam-Rudloff E, Borrebaeck CAK, Bourbeillon J, Bradbury ARM, de Daruvar A, Dübel S, Frank R, Gibson TJ, Gold L, Haslam N, Herberg FW, Hiltke T, Hoheisel JD, Kerrien S, Koegl M, Konthur Z, Korn B, Landegren U, Montecchi-Palazzi L, Palcy S, Rodriguez H, Schweinsberg S, Sievert V, Stoevesandt O, Taussig MJ, Ueffing M, Uhlén M, van der Maarel S, Wingren C, Woollard P, Sherman DJ, Hermjakob H. A community standard format for the representation of protein affinity reagents. Mol Cell Proteomics. 2010, 9(1):1-10.

Halldórsdóttir ES, Jaroszewski JW, Olafsdottir ES. Acetylcholinesterase inhibitory activity of lycopodane-type alkaloids from the Icelandic Lycopodium annotinum ssp. alpestre. Phytochemistry. 2010, 71(2-3):149-157.

Hansen GL, Sørensen M, Theilade I, Mølgaard P. Asháninka medicinal plants: a case study from the native community of Bajo Quimiriki, Junín, Peru. J Ethnobiol Ethnomed. 2010, 6(21).

Hansen KB, Mullasseril P, Dawit S, Kurtkaya NL, Yuan H, Vance KM, Orr AG, Kvist T, Ogden KK, Le P, Vellano KM, Lewis I, Kurtkaya S, Du Y, Qui M, Murphy TJ, Snyder JP, Bräuner-Osborne H, Traynelis SF. Implementation of a fluorescence-based screening assay identifies histamine H3 receptor antagonists clobenpropit and iodophenpropit as subunit-selective N-methyl-D-aspartate receptor antagonists. J Pharmacol Exp Ther (JPET). 2010, 333(3):650-662.

Holman L, Jørgensen CG, Nielsen J, D'Ettorre P. Identification of an ant queen pheromone regulating worker sterility. Proc R Soc B. 2010, 277(1701):3793-3800.

Ihrmark K, Asmail N, Ubhayasekera W, Melin P, Stenlid J, Karlsson M. Comparative molecular evolution of Trichoderma chitinases in response to mycoparasitic interactions. Evol Bioinform Online. 2010, 6:1-26.

Jaroszewski JW. Hyphenated NMR, methods and applications. I: Lindon J, Tranter G, Koppenaal D, Eds. Encyclopedia of spectroscopy and spectrometry. Vol 1, 2nd ed. Oxford: Academic Press. 2010, s. 979-983.

Jensen AA, Bergmann ML, Sander T, Balle T. Ginkgolide X is a potent antagonist of anionic Cys-loop receptors with a unique selectivity profile at glycine receptors. J Biol Chem. 2010, 285(13):10141-10153.

Jensen MH, Toft KN, David G, Havelund S, Pérez J, Vestergaard B. Time-resolved SAXS measurements facilitated by online HPLC buffer exchange. J Synchrotron Radiat. 2010, 17(6):769-773.

Jäger AK, Saaby L, Kudsk DS, Witt KC, Mølgaard P. Short communication: Influence of pasteurization on the active compounds in medicinal plants to be used in dairy products. J Dairy Sci. 2010, 93(6):2351-2353.

Kesting JR, Huang J, Sørensen D. Identification of adulterants in a Chinese herbal medicine by LC-HRMS and LC-MS-SPE/NMR and comparative in vivo study with standards in a hypertensive rat model. J Pharm Biomed Anal. 2010, 51(3):705-711.

Koradia VS, Lopez de Diego H, Frydenvang KA, Ringkjøbing-Elema M, Müllertz A, Bond AD, Rantanen J. Solid forms of amlodipine besylate: Physiochemical, structural, and thermodynamic characterization. Cryst Growth Des. 2010, 10(12):5279-5290.

Kristensen JL, Püschl A, Jensen M, Risgaard R, Christoffersen CT, Bang-Andersen B, Balle T. Exploring the neuroleptic substituent in octoclothepin: Potential ligands for positron emission tomography with subnanomolar affinity for α1-adrenoceptors. J Med Chem. 2010, 53(19):7021-7034.

Krogsgaard-Larsen N, Jensen AA, Kehler J. Novel 7-phenylsulfanyl-1,2,3,4,10,10a-hexahydro-pyrazino[1,2-a]indoles as dual serotonin 5-HT2C and 5-HT6 receptor ligands. Bioorg Med Chem Lett. 2010,  20(18):5431-5433.

Krogsgaard-Larsen N, Begtrup M, Frydenvang KA, Kehler J. Syntheses of aza-analogous iso-ergoline scaffolds using carbene mediated C-H insertion. Tetrahedron. 2010, 66(47):9297-9303.

Lauridsen MB, Bliddal H, Christensen R, Danneskiold-Samsøe B, Bennett R, Keun H, Lindon JC, Nicholson JK, Dorff MH, Jaroszewski JW, Hansen SH, Cornett C. 1H NMR spectroscopy-based interventional metabolic phenotyping: a cohort study of rheumatoid arthritis patients. J Proteome Res. 2010, 9(9):4545-4553.

Lolli ML, Giordano C, Pickering DS, Rolando B, Hansen KB, Foti A, Contreras-Sanz A, Amir A, Fruttero R, Gasco A, Nielsen B, Johansen TN. 4-hydroxy-1,2,5-oxadiazol-3-yl moiety as bioisoster of the carboxy function. Synthesis, ionization constants, and molecular pharmacological characterization at ionotropic glutamate receptors of compounds related to glutamate and its homologues. J Med Chem. 2010, 53(10):4110-4118.

López V, Jäger AK, Akerreta S, Cavero RY, Calvo MI. Antioxidant activity and phenylpropanoids of Phlomis lychnitis L.: A traditional herbal tea. Plant Foods Hum Nutr. 2010, 65(2):179-185.

López V, Martín S, Gómez-Serranillos MP, Carretero ME, Jäger AK, Calvo MI. Neuroprotective and neurochemical properties of mint extracts. Phytother Res. 2010, 24(6):869-874.

Mellergaard Larsen M, Adsersen A, Davis AP, Lledó MD, Jäger AK, Rønsted NAH. Using a phylogenetic approach to selection of target plants in drug discovery of acetylcholinesterase inhibiting alkaloids in Amaryllidaceae tribe Galantheae. Biochem Syst Ecol. 2010, 38(5):1026-1034.

Mosbæk CR, Nolan D, Persson E, Svergun DI, Bukrinsky JT, Vestergaard B. Extensive small-angle X-ray scattering studies of blood coagulation factor VIIa reveal interdomain flexibility. Biochemistry. 2010, 49(45):9739-9745.

Mosley CA, Acker TM, Hansen KB, Mullasseril P, Andersen KT, Le P, Vellano KM, Bräuner-Osborne H, Liotta DC, Traynelis SF. Quinazolin-4-one derivatives: A novel class of noncompetitive NR2C/D subunit-selective N-methyl-D-aspartate receptor antagonists. J Med Chem. 2010, 53(15):5476-5490.

Møller HA, Sander T, Kristensen JL, Nielsen B, Krall J, Bergmann ML, Christiansen B, Balle T, Jensen AA, Frølund BF. Novel 4-(piperidin-4-yl)-1-hydroxypyrazoles as γ-aminobutyric acidA receptor ligands: synthesis, pharmacology, and structure-activity relationships. J Med Chem. 2010, 53(8):3417-3421.

Neergaard JS, Rasmussen HB, Stafford GI, van Staden J, Jäger AK. Serotonin transporter affinity of (-)-loliolide, a monoterpene lactone from Mondia whitei. S Afr J Bot. 2010, 76(3):593-596.

Nielsen AL, Jørgensen FS, Olsen L, Christensen SF, Benie AJ, Bjørnholm T, St. Hilaire PM. A diversity optimized combinatorial library for the identification of Fc-fragment binding ligands. Biopolymers. 2010, 94(2):192-205.

Nielsen PE. Gene targeting and expression modulation by peptide nucleic acids (PNA). Curr Pharm Des. 2010, 16(28):3118-3123.

Nielsen PE. Peptide nucleic acids (PNA) in chemical biology and drug discovery. Chem Biodivers. 2010, 7(4):786-804.

Nielsen PE. Targeted gene repair facilitated by peptide nucleic acids (PNA). ChemBioChem. 2010, 11(15):2073-2076.

Nielsen SD, Smith G, Begtrup M, Kristensen JL. Amination of aryl iodides using a fluorous-tagged ammonia equivalent. Eur J Org Chem. 2010, 2010(19):3704-3710.

Nielsen SD, Smith G, Begtrup M, Kristensen JL. Synthesis and application of a new fluorous-tagged ammonia equivalent. Chem Eur J. 2010, 16(15):4557-4566.

Nilsson Lill SO, Forbes A, Donoghue P, Verdolino V, Wiest O, Rydberg P, Norrby P. Application of Q2MM to stereoselective reactions. Curr Org Chem. 2010, 14(15):1629-1645.

Nyberg NT, Nielsen MBO, Jaroszewski JW. Metabolic trajectories based on 1H NMR spectra of urines from sheep exposed to nutritional challenges during prenatal and early postnatal life. Metabolomics. 2010, 6(4):489-496.

Olesen UH, Petersen JG, Garten A, Kiess W, Yoshino J, Imai S, Christensen MK, Fristrup P, Thougaard AV, Björkling F, Jensen PB, Nielsen SJ, Sehested M. Target enzyme mutations are the molecular basis for resistance towards pharmacological inhibition of nicotinamide phosphoribosyltransferase. BMC Cancer. 2010, 10:677. 

Olsen CA, Ziegler HL, Nielsen HM, Frimodt-Møller N, Jaroszewski JW, Franzyk H. Antimicrobial, hemolytic, and cytotoxic activities of β-peptoid-peptide hybrid oligomers: Improved properties compared to natural AMPs. ChemBioChem. 2010, 11(10):1356-1360.

Olsen CA. Peptoid-Peptide hybrid backbone architectures. ChemBioChem. 2010, 11(2):152-160.

Omkvist DH, Larsen SB, Nielsen CU, Steffansen B, Olsen L, Jørgensen FS, Larsen BB. A quantitative structure-activity relationship for translocation of tripeptides via the human proton-coupled peptide transporter, hPEPT1 (SLC15A1). AAPS Journal. 2010, 12(3):385-396.

Ottesen LK, Jaroszewski JW, Franzyk H. Ring opening of a resin-bound chiral aziridine with phenol nucleophiles. J Org Chem. 2010, 75(15):4983-4991.

Owczarek S, Kiryushko D, Larsen MH, Kastrup JS, Gajhede M, Sandi C, Berezin V, Bock E, Soroka V. Neuroplastin-55 binds to and signals through the fibroblast growth factor receptor. FASEB J. 2010, 24(4):1139-1150.

Palner M, McCormick P, Gillings N, Begtrup M, Wilson AA, Knudsen GM. Radiosynthesis and ex vivo evaluation of (R)-(-)-2-chloro-N-[1-11C-propyl]n-propylnorapomorphine: . Nucl Med Biol. 2010, 37(1):35-40.

Pedersen ME, Baldwin RA, Niquet J, Stafford GI, van Staden J, Wasterlain CG, Jäger AK. Anticonvulsant effects of Searsia dentata (Anacardiaceae) leaf extract in rats. Phytother Res. 2010, 24(6):924-927.

Pedersen MHF, Høg S, Wellendorph P, Martiny L. Radioiododestannyllation of novel GHB neuroreceptor ligands. Paper presented at 10th International symposium on the synthesis and applications of isotopes and isotopically labelled compounds, Chicago, USA 14. - 18. June, 2009. J Labelled Comp Radiopharm. 2010, 53(5-6):318-320, John/Wiley & Sons Ltd.

Poongavanam V, Olsen L, Jørgensen FS, Vermeulen NPE, Oostenbrink C. Computational prediction of binding affinity for CYP1A2-ligand complexes using empirical free energy calculations. Drug Metab Dispos. 2010, 38(8):1347-1354.

Rasmussen P, Nyberg N, Jaroszewski JW, Krogh-Madsen R, Secher NH, Quistorff B. Brain nonoxidative carbohydrate consumption is not explained by export of an unknown carbon source: evaluation of the arterial and jugular venous metabolome. J Cereb Blood Flow Metab. 2010, 30(6):1240-1246.

Risgaard R, Hansen KB, Clausen RP. Partial agonists and subunit selectivity at NMDA receptors. Chem Eur J. 2010, 16(47):13910-13918.

Risveden K, Dick KA, Bhand S, Rydberg P, Samuelson L, Danielsson B. Branched nanotrees with immobilized acetylcholine esterase for nanobiosensor applications. Nanotechnology. 2010, 21(5):055102 (8pp).

Rubal JJ, Moreno-Dorado FJ, Guerra FM, Jorge ZD, Galán MDC, Salido GM, Christensen SB, Søhoel H, Massanet GM. A phenylpropanoid, a slovenolide, two sulphur-containing germacranes and Ca+2-ATPase inhibitors from Thapsia villosa. Planta Med. 2010, 76(3):284-290.

Rydberg P, Gloriam DEI, Zaretzki J, Breneman C, Olsen L. SMARTCyp: A 2D method for prediction of cytochrome P450-mediated drug metabolism. ACS Med Chem Lett. 2010, 1(3):96-100.

Rydberg P, Gloriam DEI, Olsen L. The SMARTCyp cytochrome P450 metabolism prediction server. Bioinformatics. 2010, 26(23):2988-2989.

Sabbatini P, Wellendorph P, Høg S, Pedersen MHF, Bräuner-Osborne H, Martiny L, Frølund BF, Clausen RP. Design, synthesis, and in vitro pharmacology of new radiolabeled γ-hydroxybutyric acid analogues including photolabile analogues with irreversible binding to the high-affinity γ-hydroxybutyric acid binding sites. J Med Chem. 2010, 53(17):6506-6510.

Sander T, Bruun AT, Balle T. Docking to flexible nicotinic acetylcholine receptors: A validation study using the acetylcholine binding protein. J Mol Graph Model. 2010;29(3):415-424.

Skottrup PD. Small biomolecular scaffolds for improved biosensor performance. Anal Biochem. 2010, 406(1):1-7.

Skottrup PD, Hansen MF, Lange JM, Deryabina M, Svendsen WE, Jakobsen MH, Dufva M. Superparamagnetic bead interactions with functionalized surfaces characterized by an immunomicroarray . Acta Biomater. 2010, 6(10):3936-3946.

Skovstrup S, Taboureau O, Bräuner-Osborne H, Jørgensen FS. Homology modelling of the GABA transporter and analysis of tiagabine binding. ChemMedChem. 2010, 5(7):986-1000.

Skytte DM, Møller JV, Liu H, Nielsen HØ, Svenningsen LE, Jensen CM, Olsen CE, Christensen SB. Elucidation of the topography of the thapsigargin binding site in the sarco-endoplasmic calcium ATPase. Bioorg Med Chem. 2010, 18(15):5634-5646.

Skytte DM, Frydenvang KA, Hansen L, Nielsen PG, Jaroszewski JW. Synthesis and characterization of an epimer of tacrolimus, an immunosuppressive drug. J Nat Prod. 2010, 73(4):776-779.

Smajilovic S, Schaal-Jensen R, Jabbari R, Smajilovic U, Haunso S, Tfelt-Hansen J. Effect of intermittent versus continuous parathyroid hormone in the cardiovascular system of rats. Open Cardiovasc Med J. 2010, 4:110-116.

Sooriyaarachchi S, Ubhayasekera W, Park C, Mowbray SL. Conformational changes and ligand recognition of Escherichia coli D-xylose binding protein revealed. J Mol Biol. 2010, 402(4):657-668.

Stanley NJ, Pedersen DS, Nielsen B, Kvist T, Mathiesen JM, Bräuner-Osborne H, Taylor DK, Abell AD. 1,2,3-triazolyl amino acids as AMPA receptor ligands. Bioorg Med Chem Lett. 2010, 20(24):7512-7515.

Stanley NJ, Hutchinson MR, Kvist T, Nielsen B, Mathiesen JM, Bräuner-Osborne H, Avery TD, Tiekink ERT, Pedersen DS, Irvine RJ, Abell AD, Taylor DK. A new metabotropic glutamate receptor agonist with in vivo anti-allodynic activity. Bioorg Med Chem. 2010, 18(16):6089-6098.

Stanstrup J, Schmidt JS, Rasmussen HB, Mølgaard P, Guzmán A, Stærk D. Bisbenzylisoquinoline alkaloids as markers of Atherospermataceae: tetrandrine and fangchinoline from Laureliopsis philippiana. Biochem Syst Ecol. 2010, 38(3):450-453.

Stanstrup J, Rusch A, Agnolet S, Rasmussen HB, Mølgaard P, Van Staden J, Stafford GI, Stærk D. Itoside A and 4-hydroxytremulacin from Dovyalis caffra and Dovyalis zeyheri. Biochem Syst Ecol. 2010, 38(3):346-348.

Sun W, Parry S, Ubhayasekera W, Engström Å, Dell A, Schedin-Weiss S. Further insight into the roles of the glycans attached to human blood protein C inhibitor. Biochem Biophys Res Commun. 2010, 403(2):198-202.

Thorsen TS, Madsen KL, Rebola N, Rathje M, Anggono V, Bach A, Moreira IS, Stuhr-Hansen N, Dyhring T, Peters D, Beuming T, Huganir R, Weinstein H, Mulle C, Strømgaard K, Rønn LCB, Gether U. Identification of a small-molecule inhibitor of the PICK1 PDZ domain that inhibits hippocampal LTP and LTD. Proc Natl Acad Sci USA (PNAS). 2010, 107(1):413-418.

Wang X, Hald H, Ernst HA, Egebjerg J, Christensen KV, Gajhede M, Kastrup JS, Mirza OA. Over-expression, purification and characterization of an Asc-1 homologue from Gloeobacter violaceus. Protein Expr Purif. 2010, 71(2):179-183.

Wellendorph P, Høg S, Sabbatini P, Pedersen MHF, Martiny L, Knudsen GM, Frølund BF, Clausen RP, Bräuner-Osborne H. Novel radioiodinated γ-hydroxybutyric acid analogues for radiolabeling and photolinking of high-affinity γ-hydroxybutyric acid binding sites. J Pharmacol Exp Ther (JPET). 2010, 335(2):458-464.

Wellendorph P, Johansen LD, Bräuner-Osborne H. The emerging role of promiscuous 7TM receptors as chemosensors for food intake. I: Litwack G red., Incretins and insulin secretion. Amsterdam: Elsevier Inc. 2010. s. 151-184. (Vitamins & hormones).

Winther AL, Liu H, Sonntag Y, Olesen C, le Maire M, Søhoel H, Olsen CE, Christensen SB, Nissen P, Møller JV. Critical roles of hydrophobicity and orientation of side chains for inactivation of sarcoplasmic reticulum Ca2+-ATPase with thapsigargin and thapsigargin analogs. J Biol Chem. 2010, 285(37):28883-28892.

Yilmaz A, Nyberg NT, Mølgaard P, Asili J, Jaroszewski JW. 1H NMR metabolic fingerprinting of saffron extracts. Metabolomics. 2010, 6(4):511-517.

Zhu T, Ubhayasekera W, Nickolaus N, Sun W, Tingsborg S, Mowbray SL, Schedin-Weiss S. Zinc ions bind to and inhibit activated protein C. Thromb Haemost. 2010, 104(3):544-553.

PhD theses:

Bornholdt J. Ring-opening of novel N-sulfonyl activated aziridines with organocopper reagents. Copenhagen: Faculty of Pharmaceutical Sciences, 2010. 195 pp.

Hansen M. Design and synthesis of selective serotonin receptor agonists for positron emission tomography imaging of the brain. Copenhagen: Faculty of Pharmaceutical Sciences, 2010. 207 pp.

Johansen LD. Functional characterization of the G protein-coupled receptor GPRC6A. Copenhagen: Faculty of Pharmaceutical Sciences, 2010. 121 pp.

Kesting JR. HPLC-MS-SPE-NMR and other modern instrumental techniques in analysis af complex natural products mixtures. Copenhagen: Faculty of Pharmaceutical Sciences, 2010. 152 pp.

Krogsgaard-Larsen N. Carbene mediated C-H insertion into phenyl piperazine and analogous structures: An approach to synthesise polycyclic, neuroactive scaffolds. Copenhagen: Faculty of Pharmaceutical Sciences, 2010. 235 pp.

Larsen SB. Computational studies of the human peptide transporter (hPEPT1) and development of tools for virtual screening. Copenhagen: Faculty of Pharmaceutical Sciences, 2010. 111 pp.

Madsen C. Synthesis of imidazole-4(5)-acetic acid analogues: for characterizing the ionotropic GABA receptors. Copenhagen: Faculty of Pharmaceutical Sciences, 2010. 186 pp.

Mosbæk CR. Small angle X-ray scattering studies of blood coagulation factor VII and antibodies at high concentration. Copenhagen: Faculty of Pharmaceutical Sciences, 2010. 141 pp.

Ottesen LK. Development of solid-phase aziridine chemistries: Piperazine scaffolds and unnatural amino acid building blocks. Copenhagen: Faculty of Pharmaceutical Sciences, 2010. 139 pp.

Poongavanam V. Cytochrome P450 in action: Rationalization and prediction through In Silico modeling of CYP1A2 Copenhagen: Faculty of Pharmaceutical Sciences, 2010. 176 pp.

Schou SC. 2010. New discoveries in isotopic labelling of organic molecules & flow chemistry: a useful technique in organic synthesis. Copenhagen: Faculty of Pharmaceutical Sciences, 145 pp.

Other publications (In Danish):

Adsersen A, Adsersen HE. Ø-planter: Evolution og kemi. Dansk Kemi. 2010, 91(3):24-26.

Andersen J, Sørensen L, Strømgaard K, Kristensen AS. Antidepressive lægemidler: nu i 3D. Lægemiddelforskning. 2010, 25-27.

Bräuner-Osborne H. Biologiens låsesmed. Universitetsavisen. 2010(9):22-23.

Gloriam DEI, Wellendorph P, Johansen LD, Pedersen DS, Bräuner-Osborne H. Kemogenomik: Receptoren set fra lægemiddelstoffets synspunkt. Lægemiddelforskning. 2010, 28-30.

Hald H, Mirza OA. Strukturer af membranproteiner: Nøglen til rationelt lægemiddeldesign. Lægemiddelforskning. 2010, 13-15.

Kesting JR, Adsersen A, Gudiksen L. Nu kan forfalskede lægemidler afsløres. Lægemiddelforskning. 2010, 4-6.

Kristensen JL, Lohse B, Clausen RP. Histonhaler: et nyt mål inden for kræftbehandling. Lægemiddelforskning. 2010, 7-9.

Larsen SB, Jørgensen FS, Olsen L. Forbedret optagelse af lægemidler i organismen: computeren viser vejen. Dansk Kemi. 2010, 91(6/7):18-20.

Rønsted NAH, Brodin B, Christensen SB, Eriksson AH, Jäger AK. Planternes slægtskab som skattekort til nye lægemidler. Lægemiddelforskning. 2010, 19-21.

Se de fleste af de danske artikler her: Lægemiddelforskning 2010

| Flere
Institut for Medicinalkemi
Topgrafik
Denne side vedligeholdes af:
Rita Larsen
Seneste opdatering: 14.05.2012

Københavns Universitet
School of Pharmaceutical Sciences
Universitetsparken 2
2100 København Ø
CVR: 29 97 98 12

Tlf. +45 35 33 60 00
Fax 35 33 60 01
Mail farma@farma.ku.dk
Web pharmaschool.ku.dk