2012
Christensen, S. B., & Bygbjerg, I. C. (2012). Drugs for the neglected disease malaria based on natural products. I Tringali, C. (Ed.), Bioactive compounds from natural sources: natural products as lead compounds in drug discovery (2nd ed.) Kapitel 15.(p. 525-550). Boca Raton: CRC Press. Taylor & Francis Group.
Holler, J. G., Søndergaard, K., Slotved, H., Gúzman, A., & Mølgaard, P. (2012). Evaluation of the antibacterial activity of Chilean plants traditionally used for wound healing therapy against multidrug-resistant Staphylococcus aureus. Planta Medica, 78(2), 200-205.
Molander, M., Christensen, S. B., Jäger, A. K., Olsen, C. E., & Rønsted, N. A. H. (2012). 6-O-Methylkrigeine, a new Amaryllidaceae alkaloid from Nerine huttoniae Schönland. Natural Product Research, 26(1), 56-60.
2011
Adsersen, A., Mogensen, P., & Adsersen, H. E. (2011). Angiotensin-converting enzyme inhibitory activity of Viscum triflorum is host plant-dependent. Pharmaceutical Biology, 49(3), 302-305.
Bay-Smidt, M. G. K., Jäger, A. K., Krydsfeldt, K., Meerow, A. W., Stafford, G. I., van Staden, J., & Rønsted, N. A. H. (2011). Phylogenetic selection of target species in Amaryllidaceae tribe Haemantheae for acetylcholinesterase inhibition and affinity to the serotonin reuptake transport protein. South African Journal of Botany, 77(1), 175-183.
Campbell-Tofte, J. I. A., Mølgaard, P., Josefsen, K., Abdallah, Z., Hansen, S. H., Cornett, C., Mu, H., Richter, E., Petersen, H. W., Nørregaard, J. C., & Winther, K. (2011). Randomized and double-blinded pilot clinical study of the safety and anti-diabetic efficacy of the Rauvolfia-Citrus tea, as used in Nigerian Traditional Medicine. Journal of Ethnopharmacology, 133(2), 402-411.
Gloriam, D. E., Wellendorph, P., Johansen, L. D., Thomsen, A. R. B., Phonekeo, K., Pedersen, D. S., & Bräuner-Osborne, H. (2011). Chemogenomic discovery of allosteric antagonists at the GPRC6A receptor. Chemistry & Biology, 18(11), 1489-1498.
Grosso, C., Vinholes, J., Silva, L. R., Guedes de Pinho, P., Goncalves, R. F., Valentao, P., Jäger, A. K., & Andrade, P. B. (2011). Chemical composition and biological screening of Capsella bursa-pastoris. Revista Brasileira de Farmacognosia (Brazilian Journal of Pharmacognosy), 21(4), 635-644.
Hein-Kristensen, L., Knapp, K. M., Franzyk, H., & Gram, L. (2011). Bacterial membrane activity of α-peptide/β-peptoid chimeras: influence of amino acid composition and chain length on the activity against different bacterial strains. B M C Microbiology, 11(1), 144.
Ioset, K. N., Nyberg, N. T., Van Diermen, D., Malnoe, P., Hostettmann, K., Shikov, A. N., & Jaroszewski, J. W. (2011). Metabolic profiling of Rhodiola rosea rhizomes by 1H NMR spectroscopy. Phytochemical Analysis, 22(2), 158-165.
Johansen, K. T., Wubshet, S. G., Nyberg, N. T., & Jaroszewski, J. W. (2011). From retrospective assessment to prospective decisions in natural product isolation: HPLC-SPE-NMR analysis of Carthamus oxyacantha. Journal of Natural Products, 74(11), 2454-2461.
Jäger, A. K., & Saaby, L. (2011). Flavonoids and the CNS. Molecules, 16(2), 1471-1485.
Karim, N., Gavande, N., Wellendorph, P., Johnston, G. A. R., Hanrahan, J. R., & Chebib, M. (2011). 3-Hydroxy-2'-methoxy-6-methylflavone: A potent anxiolytic with a unique selectivity profile at GABAA receptor subtypes. Biochemical Pharmacology, 82(12), 1971-1983.
Kesting, J. R., Johansen, K. T. & Jaroszewski, J. W. (2011). Hyphenated NMR techniques. In: Dingley, A. J. & Pascal, S. M., eds., Biomolecular NMR Spectroscopy. Amsterdam: IOS Press; pp. 413-434.
Kesting, J. R, Olsen,L., Staerk, D., Tejesvi, M. V., Kini, K. R., Prakash,H. S., & Jaroszewski, J. W. (2011). Production of unusual dispiro metabolites in Pestalotiopsis virgatula endophyte cultures: HPLC-SPE-NMR, electronic circular dichroism, and time-dependent density-functional computation study. Journal of Natural Product, 74(10), 2206-2215, doi: 10.1021/np2005665.
López, V., Jäger, A. K., Akerreta, S., Cavero, R. Y., & Calvo, M. I. (2011). Pharmacological properties of Anagallis arvensis L. ("scarlet pimpernel") and Anagallis foemina Mill. ("blue pimpernel") traditionally used as wound healing remedies in Navarra (Spain). Journal of Ethnopharmacology, 134(3), 1014-1017.
Mahmmoud, Y. A., & Christensen, S. B. (2011). Oleic and linoleic acids are active principles in Nigella sativa and stabilize an E2P conformation of the Na,K-ATPase. Fatty acids differentially regulate cardiac glycoside interaction with the pump. Biochimica et Biophysica Acta, 1808(10), 2413-2420.
Mølgaard, P., Holler, J. G., Asar, B., Liberna, I., Rosenbæk, L. B., Jebjerg, C. P., Jørgensen, L., Lauritzen, J., Guzman, A., Adsersen, A., & Simonsen, H. T. (2011). Antimicrobial evaluation of Huilliche plant medicine used to treat wounds. Journal of Ethnopharmacology, 138(1), 219-227.
Nikolajsen, T., Nielsen, F., Rasch, V., Sørensen, P. H., Ismail, F., Kristiansen, U., & Jäger, A. K. (2011). Uterine contraction induced by Tanzanian plants used to induce abortion. Journal of Ethnopharmacology, 137(1), 921-925.
Nordly, P. J., Korsholm, K. S., Pedersen, E. A., Khilji, T. S., Franzyk, H., Jørgensen, L., Nielsen, H. M., Agger, E. M., & Foged, C. (2011). Incorporation of a synthetic mycobacterial monomycoloyl glycerol analogue stabilizes dimethyldioctadecylammonium liposomes and potentiates their adjuvant effect in vivo. European Journal of Pharmaceutics and Biopharmaceutics, 77(1), 89-98.
Saaby, L., Jäger, A. K., Moesby, L., Hansen, E. W., & Christensen, S. B. (2011). Isolation of immunomodulatory triterpene acids from a standardized rose hip powder (Rosa canina L.). Phytotherapy Research, 25(2), 195-201.
Saaby, L., & Jäger, A. K. (2011). Ubiquitous plant compounds disturb cell-based assays. Journal of Ethnopharmacology, 137(1), 942-943.
Stefkov, G., Kulevanova, S., Miova, B., Dinevska-Kjovkarovska, S., Mølgaard, P., Jäger, A. K., & Josefsen, K. (2011). Effects of Teucrium polium spp. capitatum flavonoids on the lipid and carbohydrate metabolism in rats. Pharmaceutical Biology, 49(9), 885-892.
Søvsø Jensen, B., Christensen, S. B., Jäger, A. K., & Rønsted, N. A. H. (2011). Amaryllidaceae alkaloids from the Australasian tribe Calostemmateae with acetylcholinesterase inhibitory activity. Biochemical Systematics and Ecology, 39(2), 153-155.
Vandecaetsbeek, I., Christensen, S. B., Liu, H., van Veldhoven, P. P., Waelkens, E., Eggermont, J., Raeymaekers, L., Møller, J. V., Nissen, P., Wuytack, F., & Vangheluwe, P. (2011). Thapsigargin affinity purification of intracellular P2A-type Ca2+ ATPases. Biochimica et Biophysica Acta, 1813(5), 1118-1127.
Yilmaz, A., Nyberg, N. T., & Jaroszewski (2011). Metabolic profiling based on two-dimensional J-resolved 1H NMR data and parallel factor analysis. Analytical Chemistry,83(21), 8278-8285, doi: 10.1021/ac202089g.
2010
Abdelgadir, H. A., Jäger, A. K., Johnson, S. D., & van Staden, J. (2010). Influence of plant growth regulators on flowering, fruiting, seed oil content, and oil quality of Jatropha curcas. South African Journal of Botany, 76(3), 440-446.
Agnolet, S., Jaroszewski, J. W., Verpoorte, R., & Staerk D. (2010). 1H NMR-based metabolomics combined with HPLC-PDA-MS-SPE-NMR for investigation of standardized Ginkgo biloba preparations. Metabolomics, 6(2), 292-302.
Emami, S. A., Afsharypuor, S., Asili, J., & Sairafianpour, M. (2010). Chemical composition of the essential oils from Iranian conifers. Part I: Aroma profiles of leaves and fruits of Juniperus polycarpos var. polycarpos (Cupressaceae). Journal of Essential Oil Research, 22(2), 103-106.
Frølund, S.; Bella, A., Kristensen, A. S., Ziegler, H. L., Witt, M., Olsen, C. A., Strømgaard, K., Franzyk, H., & Jaroszewski, J. W. (2010). Assessment of structurally diverse philanthotoxin analogues for inhibitory activity on ionotropic glutamate receptor subtypes: Discovery of nanomolar, nonselective, and use-dependent antagonists. Journal of Medicinal Chemistry, 53(20), 7441-7451.
Halldorsdottir, E. S., Jaroszewski, J. W., & Olafsdottir, E. S. (2010). Acetylcholinesterase inhibitory activity of lycopodane-type alkaloids from the Icelandic Lycopodium annotinum ssp. alpestre. Phytochemistry, 71(2), 149-157.
Hansen, G. L., Sørensen, M., Theilade, I., & Mølgaard, P. (2010). Asháninka medicinal plants: a case study from the native community of Bajo Quimiriki, Junín, Peru. Journal of Ethnobiology and Ethnomedicine, 6(21).
Jaroszewski, J. W. (2010). Hyphenated NMR - Methods and Applications. In: Lindon, J., Tranter, G., & Koppenaal, D., eds, Encyclopedia of Spectroscopy and Spectrometry, 2nd edition, Vol 1. Oxford: Elsevier; pp. 979–983.
Jäger, A. K., Saaby, L., Kudsk, D. S., Witt, K. C., & Mølgaard, P. (2010). Influence of pasteurization on the active compounds in medicinal plants to be used in dairy products. Journal of Dairy Science, 93(6), 2351-2353.
Kesting, J. R., Huang, J., & Sørensen, D. (2010). Identification of adulterants in a Chinese herbal medicine by LC-HRMS and LC-MS-SPE/NMR and comparative in vivo study with standards in a hypertensive rat model. Journal of Pharmaceutical and Biomedical Analysis, 51(3), 705-711.
Lauridsen, M. B., Bliddal, H., Christensen, R., Danneskiold-Samsøe, B. Bennett, R., Keun, H., Lindon, J. C., Nicholson, J. K., Dorff, M. H., Jaroszewski, J. W., Hansen, S. H., & Cornett, C. (2010). 1H NMR spectroscopy-based interventional metabolic phenotyping: A cohort study of rheumatoid arthritis patients. Journal of Proteome Research, 9(9), 4545-4553.
López, V., Jäger, A. K., Akerreta, S., Cavero, R. Y., & Calvo, M. I. (2010). Antioxidant activity and phenylpropanoids of Phlomis lychnitis L.: A traditional herbal tea. Plant Foods for Human Nutrition, 65(2), 179-185.
López, V., Martín, S., Gómez-Serranillos, M. P., Carretero, M. E., Jäger, A. K., & Calvo, M. I. (2010). Neuroprotective and neurochemical properties of mint extracts. Phytotherapy Research, 24(6), 869-874.
Mellergaard Larsen, M., Adsersen, A., Davis, A. P., Lledó, M. D., Jäger, A. K., & Rønsted, N. A. H. (2010). Using a phylogenetic approach to selection of target plants in drug discovery of acetylcholinesterase inhibiting alkaloids in Amaryllidaceae tribe Galantheae. Biochemical Systematics and Ecology, 38(5), 1026-1034.
Neergaard, J. S., Rasmussen, H. B., Stafford, G. I., van Staden, J., & Jäger, A. K. (2010). Serotonin transporter affinity of (–)-loliolide, a monoterpene lactone from Mondia whitei. South African Journal of Botany, 76(3), 593-596.
Nyberg, N. T., Nielsen, M. O., & Jaroszewski, J. W. (2010). Metabolic trajectories based on 1H NMR spectra of urines from sheep exposed to nutritional challenges during prenatal and early postnatal life. Metabolomics, 6(4), 489-496. Article featured on the journal cover
Olsen, C. A., Ziegler, H. L., Nielsen, H. M., Frimodt-Møller, N., Jaroszewski, J. W., & Franzyk, H. (2010). Antimicrobial, hemolytic, and cytotoxic activities of β-peptoid-peptide hybrid oligomers: Improved properties compared to natural AMPs. ChemBioChem, 11(10), 1356-1360. Article featured on the inside cover of the journal
Olsen, C. A. (2010). Peptoid-Peptide hybrid backbone architectures. ChemBioChem, 11(2), 152-160.
Ottesen, L. K., Jaroszewski, J. W., & Franzyk, K. (2010). Ring opening of a resin-bound chiral aziridine with phenol nucleophiles. Journal of Organic Chemistry, 75(15), 4983-4991.
Pedersen, M. E., Baldwin, R. A., Niquet, J., Stafford, G. I., van Staden, J., Wasterlain, C. G., & Jäger, A. K. (2010). Anticonvulsant effects of Searsia dentata (Anacardiaceae) leaf extract in rats. Phytotherapy Research, 24(6), 924-927.
Rasmussen, P., Nyberg, N. T., Jaroszewski, J. W., Krogh-Madsen, R., Secher N. H., & Quistorff, B. (2010). Brain nonoxidative carbohydrate consumption is not explained by export of an unknown carbon source: Evaluation of the arterial and jugular venous metabolome. Journal of Cerebral Blood Flow & Metabolism, 30(6), 1240-1246.
Rubal, J. J., Moreno-Dorado, F. J., Guerra, F. M., Jorge, Z. D., Galán, M. D. C., Salido, G. M., Christensen, S. B., Søhoel, H., & Massanet, G. M. (2010). A phenylpropanoid, a slovenolide, two sulphur-containing germacranes and Ca+2-ATPase inhibitors from Thapsia villosa. Planta Medica, 76(3), 284-290.
Sabbatini, P., *Wellendorph, P., Høg, S., Pedersen, M. H. F., Bräuner-Osborne, H., Martiny, L., Frølund, B. F., & Clausen, R. P. (2010). Design, synthesis, and in vitro pharmacology of new radiolabeled γ-hydroxybutyric acid analogues including photolabile analogues with irreversible binding to the high-affinity γ-hydroxybutyric acid binding sites. Journal of Medicinal Chemistry, 53(17), 6506-6510. *member of the Molecular Pharmacology Research group when the manuscript was prepared
Skytte, D. M., Møller, J. V., Liu, H., Nielsen, H. Ø., Svenningsen, L. E., Jensen, C. M., Olsen, C. E., & Christensen, S. B. (2010). Elucidation of the topography of the thapsigargin binding site in the sarco-endoplasmic calcium ATPase. Bioorganic & Medicinal Chemistry, 18(15), 5634-5646.
Skytte, D. M., Frydenvang, K., Hansen, L., Nielsen, P. G., & Jaroszewski, J. W. (2010). Synthesis and characterization of an epimer of tacrolimus, an immunosuppressive drug. Journal of Natural Products, 73(4), 776-779.
Stanstrup, J., Schmidt, J. S., Rasmussen, H. B., Mølgaard, P., Guzmán, A., & Stærk, D. (2010). Bisbenzylisoquinoline alkaloids as markers of Atherospermataceae: tetrandrine and fangchinoline from Laureliopsis philippiana. Biochemical Systematics and Ecology, 38(3), 450-453.
Stanstrup, J., Rusch, A., Agnolet, S., Rasmussen, H. B., Mølgaard, P., van Staden, J., Stafford, G. I., & Stærk, D. (2010) Itoside A and 4-hydroxytremulacin from Dovyalis caffra and Dovyalis zeyheri. Biochemical Systematics and Ecology, 38(3), 346-348.
*Wellendorph, P., Høg, S., Sabbatini, P., Pedersen, M. H. F., Martiny, L., Knudsen, G. M., Frølund, B. F., Clausen, R. P., & Bräuner-Osborne, H. (2010). Novel radioiodinated γ-hydroxybutyric acid analogues for radiolabeling and photolinking of high-affinity γ-hydroxybutyric acid binding sites. Journal of Pharmacology and Experimental Therapeutics, 335(2), 458-464. *member of the Molecular Pharmacology Research group when the manuscript was prepared
*Wellendorph, P., Johansen, L. D., & Bräuner-Osborne, H. (2010). The emerging role of promiscuous 7TM receptors as chemosensors for food intake. In: Litwack, G., ed, Incretins and Insulin Secretion. Amsterdam: Elsevier; pp. 151-184. *member of the Molecular Pharmacology Research group when the manuscript was prepared
Winther, A. L., Liu, H., Sonntag, Y., Olesen, C., le Maire, M., Søhoel, H., Olsen, C. E., Christensen, S. B., Nissen, P., & Møller, J. V. (2010). Critical roles of hydrophobicity and orientation of side chains for inactivation of sarcoplasmic reticulum Ca2+-ATPase with thapsigargin and thapsigargin analogs. Journal of Biological Chemistry, 285(37), 28883-28892.
Yilmaz, A., Nyberg, N. T., Mølgaard, P., Asili, J., & Jaroszewski, J. W. (2010). 1H NMR metabolic fingerprinting of saffron extracts. Metabolomics, 6(4), 511-517.
2009
Crestey, F., Witt, M., Jaroszewski, J. W., & Franzyk, H. (2009). Expedite protocol for construction of chiral regioselectively N-protected monosubstituted piperazine, 1,4-diazepane, and 1,4-diazocane building blocks. Journal of Organic Chemistry, 74(15), 5652-5655.
Christensen, S. B., Skytte, D. M., Denmeade, S. R., Dionne, C., Møller, J. V., Nissen, P., & Isaacs, J. T. (2009). A Trojan horse in drug development: Targeting of thapsigargins towards prostate cancer cells. Anti-Cancer Agents in Medicinal Chemistry, 9(3), 276-294.
Griend, D. J. V., Antony, L., Dalrymple, S. L., Xu, Y., Christensen, S. B., Denmeade, S. R., & Isaacs, J. T. (2009). Amino acid containing thapsigargin analogues deplete androgen receptor protein via synthesis inhibition and induce the death of prostate cancer cells. Molecular Cancer Therapeutics, 8(5), 1340-1349.
Jäger, A. K., Krydsfeldt, K., & Rasmussen, H. B. (2009). Bioassay-guided isolation of apigenin with GABA-benzodiazepine activity from Tanacetum parthenium. Phytotherapy Research, 23(11), 1642-1644.
Kesting, J. R., Stærk, D., Tejesvi, M. V., Harishchandra, S. P., & Jaroszewski, J. W. (2009). HPLC-SPE-NMR identification of a novel metabolite containing the benzo[c]oxepin skeleton from the endophytic fungus Pestalotiopsis virgatula culture. Planta Medica, 75(10), 1104-1106.
Kesting, J. R., Tolderlund, I., Pedersen, A. F., Witt, M., Jaroszewski, J. W., & Stærk, D. (2009). Piperidine and tetrahydropyridine alkaloids from Lobelia siphilitica and Hippobroma longiflora. Journal of Natural Products, 72(2), 312-315.
Larsen, J. T., Stærk, D., Cornett, C., Hansen, S. H., & Jaroszewski, J. W. (2009). Identification of reaction products between drug substances and excipients by HPLC-SPE-NMR: Ester and amide formation between citric acid and 5-aminosalicylic acid. Journal of Pharmaceutical and Biomedical Analysis, 49(3), 839-842.
Larsen, J. T., Cornett, C., Jaroszewski, J. W., & Hansen, S. H. (2009). Reaction between drug substances and pharmaceutical excipients: formation of citric acid esters and amides of carvedilol in the solid state. Journal of Pharmaceutical and Biomedical Analysis, 49(1), 11-17.
Lawaetz, A. J., Schmidt, B., Stærk, D., Jaroszewski, J. W., & Bro, R. (2009). Application of rotated PCA models to facilitate interpretation of metabolite profiles: Commercial preparations of St. John's wort. Planta Medica, 75(3), 271-279.
López, V., Martín, S., Gómez-Serranillos, M. P., Carretero, M. E., Jäger, A. K., & Calvo, M. I. (2009). Neuroprotective and neurological properties of Melissa officinalis. Neurochemical Research, 34(11), 1955-1961.
Lukwa, N., Mølgaard, P., Furu, P., & Bøgh, C. (2009). Lippia javanica (Burm F) Spreng: Its general constituents and bioactivity on mosquitoes. Tropical Biomedicine, 26(1), 85-91.
Naqishbandi, A. M., Josefsen, K., Pedersen, M. E., & Jäger, A. K. (2009). Hypoglemic activity of Iraqi Rheum ribes root extract. Pharmaceutical Biology, 47(5), 380-383.
Neergaard, J. S., Andersen, J., Pedersen, M. E., Stafford, G. I., van Staden, J., & Jäger, A. K. (2009). Alkaloids from Boophone disticha with affinity to the serotonin transporter. South African Journal of Botany, 75(2), 371-374.
Ottesen, L. K., Olsen, C. A., Witt, M., Jaroszewski, J. W., & Franzyk, H. (2009). Selectively N-protected enantiopure 2,5-disubstituted piperazines: Avoiding the pitfalls in solid-phase Fukuyama-Mitsunobu cyclizations. Chemistry: A European Journal, 15(12), 2966-2978.
Pedersen, M. E., Metzler, B., Stafford, G. I., van Staden, J., Jäger, A. K., & Rasmussen, H. B. (2009). Amides from Piper capense with CNS activity: A preliminary SAR analysis. Molecules, 14(9), 3833-3843.
Pedersen, M. E., Vestergaard, H. T., Hansen, S. L., Bah, S., Diallo, D., & Jäger, A. K. (2009). Pharmacological screening of Malian medicinal plants used against epilepsy and convulsions. Journal of Ethnopharmacology, 121(3), 472-475.
Pedersen, M. M., Chukwujekwu, J. C., Lategan, C. A., van Staden, J., Smith, P. J., & Stærk, D. (2009). Antimalarial sesquiterpene lactones from Distephanus angulifolius. Phytochemistry, 70(5), 601-607.
Saaby, L., Rasmussen, H. B., & Jäger, A. K. (2009). MAO-A inhibitory activity of quercetin from Calluna vulgaris (L.) Hull. Journal of Ethnopharmacology, 121(1), 178-181.
Simonsen, H. T., Riedel, C., Gade, L. B., Jebjerg, C., Guzman, A., & Mølgaard, P. (2009). Chemical composition and antibacterial activity of the leaf essential oil of Baccharis magellanica (Lam.) Pers. and Baccharis elaeoides Remy from Chile. Journal of Essential Oil Research, 21(4), 377-380.
Stafford, G. I., Jäger, A. K., & van Staden, J. (2009). African psychoactive plants. In: Juliana, H. R., Simon, J. E., & Ho, C., eds.. African natural plant products: New Discoveries and Challenges in Chemistry and Quality (ACS Symposium Series 1021). Washington, D. C.: American Chemical Society; pp.323-346.
Stærk, D., Kesting, J. R., Sairafianpour, M., Witt, M., Asili, J., Emami, S. A., & Jaroszewski, J. W. (2009). Accelerated dereplication of crude extracts using HPLC-PDA-MS-SPE-NMR: Quinolinone alkaloids of Haplophyllum acutifolium. Phytochemistry, 70(8), 1055-1061.
Stærk, D., Pham Thi, L., Rasmussen, H. B., Guzmán, A., & Mølgaard, P. (2009). New bisbenzylisoquinoline alkaloid from Laureliopsis philippiana. Fitoterapia, 80(2), 112-114.
Traoré-Coulibaly, M., Ziegler, H. L., Olsen, C. E., Hassanata, M., Pierre, G. I., Nacoulma, O. G., Guiguemdé, T. R., & Christensen, S. B. (2009). 19α-Hydroxy-3-oxoursa-1,12-dien-28-oic acid, an antiplasmodial triterpenoid isolated from Canthium multiflorum. Natural Product Research, 23(12), 1108-1111.
2008
Bjarnholt, N., Rook, F., Motawie, M. S., Cornett, C., Jørgensen, C., Olsen, C. E., Jaroszewski, J. W., Bak, S., & Møller, B. L. (2008). Diversification of an ancient theme: Hydroxynitrile glucosides. Phytochemistry, 69(7), 1507-1516.
Bonke, G., Vedel, L., Witt, M., Jaroszewski, J. W., Olsen, C. A., & Franzyk, H. (2008). Dimeric buiding blocks for solid-phase synthesis of α-peptide-β-peptoid chimeras. Synthesis, 2008(15), 2381-2390.
Crestey, F. L. J., Ottesen, L. K., Jaroszewski, J. W., & Franzyk, H. (2008). Efficient loading of primary alcohols onto a solid phase using a trityl bromide linker. Tetrahedron Letters, 49(41), 5890-5893.
Crestey, F. L. J., Witt, M., Frydenvang, K. A., Stærk, D., Jaroszewski, J. W., & Franzyk, H. (2008). Microwave-assisted ring-opening of activated aziridines with resin-bound amines. Journal of Organic Chemistry, 73(9), 3566-3569.
Foged, C., Franzyk, H., Bahrami, S., Frøkjær, S., Jaroszewski, J. W., Nielsen, H. M., & Olsen, C. A. (2008). Cellular uptake and membrane-destabilising properties of α-peptide/β-peptoid chimeras: lessons for the design of new cell-penetrating peptides. Biochimica et Biophysica Acta, 1778(11), 2487-2495.
Jalkanen, K., Gale, J. D., Lassen, P., Hemmingsen, L. B. S., Rodarte, A., Degtyarenko, I., Nieminen, R., Knapp-Mohammady, M., Suhai, S., & Christensen, S. B. (2008). A configurational and conformational study of aframodial and its diasteriomers via experimental and theoretical VA and VCD spectroscopies. Theoretical Chemistry Accounts, 119(1-3), 177-190.
Jäger, A. K., Petersen, K. N., Thomasen, G., & Christensen, S. B. (2008). Isolation of linoleic and α-linolenic acids as COX-1 and -2 inhibitors in rose hip. Phytotherapy Research, 22(7), 982-984.
Lauridsen, M., Maher, A. D., Keun, H., Lindon, J. C., Nicholson, J. K., Nyberg, N. T., Hansen, S. H., Cornett, C., & Jaroszewski, J. W. (2008). Application of the FLIPSY pulse sequence for increased sensitivity in 1H NMR-based metabolic profiling studies. Analytical Chemistry, 80(9), 3365-3371.
Lundgaard, N. H., Prior, R. M., Light, M. E., Stafford, G. I., van Staden, J., & Jäger, A. K. (2008). COX-1 inhibition of Heteromorpha arborescens. South African Journal of Botany, 74(2), 335-337.
Olsen, A., Prinsloo, L. C., Scott, L., & Jäger, A. K. (2008). Hyraceum, the fossilized metabolic product of rock hyraxes (Procavia capensis), shows GABA-benzodiazepine receptor affinity. South African Journal of Science, 103(11/12), 437-438.
Olsen, C. A., Lambert, M., Witt, M., Franzyk, H., & Jaroszewski, J. W. (2008). Solid-phase peptide synthesis and circular dichroism study of chiral β-peptoid homooligomers. Amino Acids, 34(3), 465-471.
Olsen, H. T., Stafford, G. I., van Staden, J., Christensen, S. B., & Jäger, A. K. (2008). Isolation of the MAO-inhibitor naringenin from Mentha aquatica L. Journal of Ethnopharmacology, 117(3), 500-502.
Pedersen, M. E., Szewczyk, B., Stachowicz, K., Wieronska, J., Andersen, J., Stafford, G. I., van Staden, J., Pilc, A., & Jäger, A. K. (2008). Effects of South African traditional medicine in animal models for depression. Journal of Ethnopharmacology, 119(3), 542-548.
Pedersen, M. E., Vestergaard, H. T., Stafford, G. I., van Staden, J., & Jäger, A. K. (2008). The effect of extracts of Searsia species on epileptiform activity in slices of the mouse cerebral cortex. Journal of Ethnopharmacology, 119(3), 538-541.
Rønsted, N. A. H., Savolainen, V., Mølgaard, P., & Jäger, A. K. (2008). Phylogenetic selection of Narcissus species for drug discovery. Biochemical Systematics and Ecology, 36(5-6), 417-422.
Rønsted, N. A. H., Weiblen, G. D., Savolainen, V., & Cook, J. M. (2008). Phylogeny, biogeography, and ecology of Ficus section Malvanthera (Moraceae). Molecular Phylogenetics and Evolution, 48(1), 12-22.
Schmidt, B., Jaroszewski, J. W., Bro, R., Witt, M., & Stærk, D. (2008). Combining PARAFAC analysis of HPLC-PDA profiles and structural characterization using HPLC-PDA-SPE-NMR-MS experiments: Commercial preparations of St. John's Wort. Analytical Chemistry, 80(6), 1978-1987.
Sheykhzade, M., Smajilovic, S., Issa, A., Haunso, S., Christensen, S. B., & Tfelt-Hansen, J. (2008). S-Petasin and butterbur lactones dilate vessels through blockage of voltage gated calcium channels and block DNA synthesis. European Journal of Pharmacology, 593(1-3), 79-86.
Skytte, D. M., Rasmussen, H. B., & Christensen, S. B. (2008). Carroll rearrangement to construct the norneolignan skeleton. Natural Product Research, 22(2), 116-123.
Sprogøe, K., Stærk, D., Ziegler, H. L., Jensen, T. H., Holm-Møller, S. B., & Jaroszewski, J. W. (2008). Combining HPLC-PDA-MS-SPE-NMR with circular dichroism for complete natural product characterization in crude extracts: Levorotatory gossypol in Thespesia danis. Journal of Natural Products, 71(4), 516-519.
Stafford, G. I., Pedersen, M. E., van Staden, J., & Jäger, A. K. (2008). Review on plants with CNS-effects used in traditional South African medicine against mental diseases. Journal of Ethnopharmacology, 119(3), 513-37.
Traoré, M., Jaroszewski, J. W., Olsen, C. E., Ouédraogo, J. B., Pierre, G. I., Nacoulma, O. G., Guiguemdé, T. R., & Christensen, S. B. (2008). A new oxygenated ursane derivative from Canthium multiflorum. Planta Medica, 74(5), 560-562.
2007
Adsersen, A., Kjølbye, A., Dall, O., & Jäger, A. K. (2007). Acetylcholinesterase and butyrylcholinesterase inhibitory compounds from Corydalis cava Schweigg. & Kort. Journal of Ethnopharmacology, 113(1), 179-182.
Adsersen, A., Smitt, U. W., Simonsen, H. T., Christensen, S. B., & Jaroszewski, J. W. (2007). Prenylated acetophenones from Melicope obscura and Melicope obtusifolia ssp. obtusifolia var. arborea and their distribution in Rutaceae. Biochemical Systematics and Ecology, 35(7), 447-453.
Alaadin, A. M., Al-Khateeb, E. H., & Jäger, A. K. (2007). Antibacterial activity of the Iraqi Rheum ribes root. Pharmaceutical Biology, 45(9), 688-690.
Bah, S., Jäger, A. K., Adsersen, A., Diallo, D., & Paulsen, B. S. (2007). Antiplasmodial and GABAA-benzodiazepine receptor binding activities of five plants used in traditional medicine in Mali, West Africa. Journal of Ethnopharmacology, 110(3), 451-457.
Campbell-Tofte, J. I. A., Hansen, H. S., Mu, H., & Mølgaard, P. (2007). Increased lipids in non-lipogenic tissues are indicators of the severity of type 2 diabetes in mice. Prostaglandins, Leukotrienes & Essential Fatty Acids, 76(1), 9-18.
Clarkson, C., Sibum, M., Mensen, R., & Jaroszewski, J. W. (2007). Evaluation of on-line solid-phase extraction parameters for hyphenated, high-performance liquid chromatography-solid-phase extraction-nuclear magnetic resonance applications. Journal of Chromatography A, 1165(1-2), 1-9.
Clarkson, C., Madikane, E. V., Hansen, S. H., Smith, P. J., & Jaroszewski, J. W. (2007). HPLC-SPE-NMR characterization of sesquiterpenes in an antimycobacterial fraction from Warburgia salutaris. Planta Medica, 73(6), 578-584.
Jäger, A. K., Almqvist, J. P., Vangsøe, S. A. K., Stafford, G. I., Adsersen, A., & van Staden, J. (2007). Compounds from Mentha aquatica with affinity to the GABA-benzodiazepine receptor. South African Journal of Botany, 73(4), 518-521.
Jäger, A. K., Eldeen, I. M. S., & van Staden, J. (2007). COX-1 and -2 activity of rose hip. Phytotherapy Research, 21(12), 1251-1252.
Khalid, S. A., Friedrichsen, G. M., Christensen, S. B., El Tahir, A., & Satti, G. M. (2007). Isolation and characterization of pristimerin as the antiplasmodial and antileishmanial agent of Maytenus senegalensis (Lam.) Exell. ARKIVOC, 2007(9), 129-134.
Lambert, M., Wolfender, J., Stærk, D., Christensen, S. B., Hostettmann, K., & Jaroszewski, J. W. (2007). Identification of natural products using HPLC-SPE combined with CapNMR. Analytical Chemistry, 79(2), 727-735.
Lauridsen, M., Hansen, S. H., Jaroszewski, J. W., & Cornett, C. (2007). Human urine as test material in 1H NMR-based metabonomics: Recommendations for sample preparation and storage. Analytical Chemistry, 79(3), 1181-1186.
Olsen, C. A., Bonke, G., Vedel, L., Adsersen, A., Witt, M., Franzyk, H., & Jaroszewski, J. W. (2007). α-Peptide/β-peptoid chimeras. Organic Letters, 9(8), 1549-1552.
Olsen, C. A., Franzyk, H., & Jaroszewski, J. W. (2007). Aziridines in parallel- and solid-phase synthesis. European Journal of Organic Chemistry, 2007(11), 1717-1724.
Olsen, C. A., Witt, M., Franzyk, H., & Jaroszewski, J. W. (2007). Solid-phase synthesis of neuroactive spider-wasp hybrid toxin analogues using a backbone amide linker. Tetrahedron Letters, 48(3), 405-408.
Prior, R. M., Lundgaard, N. H., Light, M. E., Stafford, G. I., van Staden, J., & Jäger, A. K. (2007). The polyacetylene falcarindiol with COX-1 activity isolated from Aegopodium podagraria L.. Journal of Ethnopharmacology, 113(1), 176-178.
Soelberg, J., Jørgensen, L. B., & Jäger, A. K. (2007). Hyperforin accumulates in the translucent glands of Hypericum perforatum. Annals of Botany, 99(6), 1097-1100 [Erratum 100(3), 679].
Sprogøe, K., Stærk, D., Jäger, A. K., Adsersen, A., Hansen, S. H., Witt, M., Landbo, A. R., Meyer, A. S., & Jaroszewski, J. W. (2007). Targeted natural product isolation guided by HPLC-SPE-NMR: Constituents of Hubertia species. Journal of Natural Products, 70(9), 1472-1477.
Stafford, G. I., Pedersen, P. D., Jäger, A. K., & van Staden, J. (2007). Monoamine oxidase inhibition by Southern African traditional medicinal plants. South African Journal of Botany, 73(3), 384-390.
Thygesen, L., Thulin, J., Mortensen, A., Skibsted, L. H., & Mølgaard, P. (2007). Antioxidant activity of cichoric acid and alkamides from Echinacea purpurea, alone and in combination. Food Chemistry, 101(1), 74-81.
Traoré, M., Zhai, L., Chen, M., Olsen, C. E., Odile, N., Pierres, G. I., Bosco, O. J., Robert, G. T., & Christensen, S. B. (2007). Cytotoxic kurubasch aldehyde from Trichilia emetica. Natural Product Reports, 21(1), 13-17.
Vedel, L., Bonke, G., Foged, C., Ziegler, H. L., Franzyk, H., Jaroszewski, J. W., & Olsen, C. A. (2007). Antiplasmodial and prehemolytic activities of α-peptide-β-peptoid chimeras. ChemBioChem, 8(15), 1781-1784.
2006
Adsersen, A., Gauguin, B., Gudiksen, L., & Jäger, A. K. (2006). Screening of plants used in Danish folk medicine to treat memory dysfunction for acetylcholinesterase inhibitory activity. Journal of Ethnopharmacology, 104, 418-422.
Balle, T., Begtrup, M., Jaroszewski, J. W., Liljefors, T., & Norrby, P.-O. (2006). Regioselectivity in lithiation of 1-methylpyrazole: experimental, density functional theory and multinuclear NMR study. Organic & Biomolecular Chemistry, 4, 1261-1267.
Bringmann, G., Kajahn, I., Reichert, M., Pedersen, S. E. H., Faber, J. H., Gulder, T., Brun, R., Christensen, S. B., Ponte-Sucre, A., Moll, H., Heubl, G., & Mudogo, V. (2006). Ancistrocladinium A and B, the first N,C-coupled naphthyldihydroisoquinoline alkaloids, from a Congolese Ancistrocladus species. Journal of Organic Chemistry, 71, 9348-9356.
Campbell, J. I. A., Mortensen, A., & Mølgaard, P. (2006). Tissue lipid lowering-effect of a traditional Nigerian anti-diabetic infusion of Rauwolfia vomitoria foilage and Citrus aurantium fruit. Journal of Ethnopharmacology, 104, 379-386.
Clarkson, C., Mellor, I. R., Lambert, M., & Jaroszewski, J. W. (2006). 5α-Cardenolides from Kanahia laniflora inhibit ionotropic acetylcholine receptors. Planta Medica, 72, 1418-1420.
Clarkson, C., Stærk, D., Hansen, S. H., Smith, P. J., & Jaroszewski, J. W. (2006). Discovering new natural products directly from crude extracts by HPLC-SPE-NMR: Chinane diterpenes in Harpagophytum procumbens. Journal of Natural Products, 69, 527-530.
Clarkson, C., Stærk, D., Hansen, S. H., Smith, P. J., & Jaroszewski, J. W. (2006). Identification of major and minor constituents of Harpagophytum procumbens (Devil's Claw) using HPLC-SPE-NMR and HPLC-ESIMS/APCIMS. Journal of Natural Products, 69, 1280-1288.
Elgorashi, E. E., Stafford, G. I., Jäger, A. K., & van Staden, J. (2006). Inhibition of [3H]citalopram binding to the rat brain serotonin transporter by Amaryllidaceae alkaloids. Planta Medica, 72, 470-473.
Janssen, S., Rosen, D. M., Ricklis, R. M., Dionne, C. R., Lilja, H., Christensen, S. B., Isaacs, J. T., & Denmeade, S. R. (2006). Pharmacokinetics, biodistribution, and antitumor efficacy of a human glandular kallikrein 2 (hK2)-activated thapsigargin prodrug. Prostate, 66, 358-368.
Jäger, A. K., Gauguin, B., Adsersen, A., & Gudiksen, L. (2006). Screening of plants used in Danish folk medicine to treat epilepsy and convulsions. Journal of Ethnopharmacology, 105, 294-300.
Kvist, L. P., Christensen, S. B., Rasmussen, H. B., Mejia, K., & Gonzalez, A. (2006). Identification and evaluation of Peruvian plants used to treat malaria and leishmaniasis. Journal of Ethnopharmacology, 106, 390-402.
Lambert, M., Olsen, L., & Jaroszewski, J. W. (2006). Stereoelectronic effects on 1H nuclear magnetic resonance chemical shifts in methoxybenzenes. Journal of Organic Chemistry, 71, 9449-9457.
Liu, H., Jensen, K. G., Tran, L. M., Chen, M., Zhai, L., Olsen, C. E., Søhoel, H., Denmeade, S. R., Isaacs, J. T., & Christensen, S. B. (2006). Cytotoxic phenylpropanoids and an additional thapsigargin analogue isolated from Thapsia garganica. Phytochemistry, 67, 2651-2658.
Makunga, N. P., Jäger, A. K., & van Staden, J. (2006). Improved in vitro rooting and hyperhydricity in regenerating tissues of Thapsia garganica L. Plant Cell, Tissue and Organ Culture, 86, 77-86.
Olsen, C. A., Christensen, C., Nielsen, B., Mohamed, F. M., Witt, M., Clausen, R. P., Kristensen, J. L., Franzyk, H., & Jaroszewski, J. W. (2006). Aminolysis of resin-bound N-nosylaziridine-2-carboxylic acids. Organic Letters, 8, 3371-3374.
Olsen, C. A., Mellor, I. R., Wellendorph, P., Usherwood, P. N. R., Witt, M., Franzyk, H., & Jaroszewski, J. W. (2006). Tuning wasp toxin structure for nicotinic receptor antagonism: Cyclohexylalanine-containing analogues as potent and voltage-dependent blockers. ChemMedChem, 1, 303-305. Article featured on the journal cover
Rasmussen, B., Cloarec, O., Tang, H., Stærk, D., & Jaroszewski, J. W. (2006). Multivariate analysis of integrated and full-resolution 1H-NMR spectral data from complex pharmaceutical preparations: St. John's wort. Planta Medica, 72, 556-563.
Rasmussen, B., Nkurunziza, A., Witt, M., Oketch-Rabah, H. A., Jaroszewski, J. W., & Stærk, D. (2006). Dovyalicin-type spermidine alkaloids from Dovyalis species. Journal of Natural Products, 69, 1300-1304.
Rubal, J. J., Guerra, F. M., Moreno-Dorado, F. J., Jorge, Z. D., Massanet, G. M., Søhoel, H., Smitt, U. W., Frydenvang, K., Christensen, S. B., Nielsen, C., & Eriksson, M. (2006). Sesquiterpenes from Thapsia nitida var. meridionalis and Thapsia nitida var. nitida. Journal of Natural Products, 69, 1566-1571.
Simonsen, H. T., Adsersen, A., Berthelsen, L., Christensen, S. B., Guzmán, A., & Mølgaard, P. (2006). Ethnopharmacological evaluation of radal (leaves of Lomatia hirsuta) and isolation of 2-methoxyjuglone. BMC Complementary and Alternative Medicine, 6, 1-4.
Skytte, D. M., Nielsen, S. F., Chen, M., Zhai, L., Olsen, C. E., & Christensen, S. B. (2006). Antimalarial and antiplasmodial activities of norneolignan. Syntheses and SAR. Journal of Medicinal Chemistry, 49, 436-440.
Strømgaard, K., Piazzi, L., Olsen, C. A., Franzyk, H., & Jaroszewski, J. W. (2006). Protolytic properties of polyamine wasp toxin analogues studied by 13C NMR spectroscopy. Magnetic Resonance in Chemistry, 44, 1013-1022.
Stærk, D., Lambert, M., & Jaroszewski, J. W. (2006). HPLC-NMR techniques for plant extract analysis. In: Kayser, O., & Quax, W., eds, Medicinal Plant Biotechnology. Weinheim: Wiley-VCH; pp. 29-48.
Stærk, D., Chapagain, B. P., Lindin, T., Wiesman, Z., & Jaroszewski, J. W. (2006). Structural analysis of complex saponins of Balanites aegyptiaca by 800 MHz 1H NMR spectroscopy. Magnetic Resonance in Chemistry, 44, 923-928.
Svenningsen, A. B., Madsen, K. D., Liljefors, T., Stafford, G. I., van Staden, J., & Jäger, A. K. (2006). Biflavones from Rhus species with affinity for the GABAA/benzodiazepine receptor. Journal of Ethnopharmacology, 103, 276-280.
Søhoel, H., Jensen, A.-M. L., Møller, J. V., Nissen, P., Denmeade, S. R., Isaacs, J. T., Olsen, C. E., & Christensen, S. B. (2006). Natural products as starting materials for development of second-generation SERCA inhibitors targeted towards prostate cancer cells. Bioorganic & Medicinal Chemistry, 14, 2810-2815.
Vasilev, N. P., Julsing, M. K., Koulman, A., Clarkson, C., Woerdenbag, H. J., Ionkova, I., Bos, R., Jaroszewski, J. W., Kayser, O., & Quax, W. J. (2006). Bioconversion of deoxypodophyllotoxin into epipodophyllotoxin in E. coli using human cytochrome P450 3A4. Journal of Biotechnology, 126, 383-393.
Ziegler, H. L., Staalsø, T., & Jaroszewski, J. W. (2006). Loading of erythrocyte membrane with pentacyclic triterpenes inhibits Plasmodium falciparum invasion. Planta Medica, 72, 640-642.
2005
Clarkson, C., Stærk, D., Hansen, S. H., & Jaroszewski, J. W. (2005). Hyphenation of solid-phase extraction with liquid chromatography and nuclear magnetic resonance: Application of HPLC-DAD-SPE-NMR to identification of constitutents of Kanahia laniflora. Analytical Chemistry, 77, 3547-3553.
Dalby-Brown, L., Barsett, H., Landbo, A.-K. R., Meyer, A. S., & Mølgaard, P. (2005). Synergistic antioxidative effects of alkamides, caffeic acid derivatives, and polysaccharide fractions from Echinacea purpurea on in vitro oxidation of human low-density lipoproteins. Journal of Agricultural and Food Chemistry, 53, 9413- 9423
Grace, O. M., van Staden J., & Jäger, A. K. (2005). Authentication of barks used in South African traditional healthcare with thin layer chromatography. Acta Horticulturae, 679, 71-74.
Jaroszewski, J. W. (2005). HPLC-SPE-NMR: A productivity tool for determination of natural products in plant material. In: Engelsen, S. B., Belton, P. S., & Jakobsen, H. J., eds., Magnetic Resonance in Food - the Multivariate Challenge. London: The Royal Society of Chemistry; pp. 39-46.
Jaroszewski, J. W. (2005). Hyphenated NMR methods in natural products research, part 1: Direct hyphenation. Planta Medica, 71, 691-700.
Jaroszewski, J. W. (2005). Hyphenated NMR methods in natural products research, part 2: HPLC-SPE-NMR and other new trends in NMR hyphenation. Planta Medica, 71, 795-802.
Jaroszewski, J. W., Stærk, D., Holm-Møller, S. B., Jensen, T. H., Franzyk, H., & Somanadhan, B. (2005). Naravelia zeylanica: occurrence of primary benzamides in flowering plants. Natural Product Research, 19, 291-294.
Jäger, A. K., Mohoto, S. P., van Heerden, F. R., & Viljoen, A. M. (2005). Activity of a traditional South African epilepsy remedy in the GABA-benzodiazepine receptor assay. Journal of Ethnopharmacology, 96, 603-606.
Jäger, A. K. & van Staden, J. (2005). Cyclooxygenase inhibitory activity of South African plants used against inflammation. Phytochemistry Reviews, 4, 39-46.
Jäger, A. K. (2005). Is traditional medicine better off 25 years later? Journal of Ethnopharmacology, 100, 3-4.
Jørgensen, M. R., Jaroszewski, J. W., Witt, M., & Franzyk, H. (2005). On-resin carboxy group activation of ω-amino acids in solid-phase synthesis of philanthotoxin analogues. Synthesis, 2687-2694.
Jørgensen, M. R., Olsen, C. A., Mellor, I. R., Usherwood, P. N. R., Witt, M., Franzyk H, & Jaroszewski, J. W. (2005). The effects of conformational constraints and steric bulk in the amino acid moiety of philanthotoxins on AMPAR antagonisms. Journal of Medicinal Chemistry, 48, 56-70.
Lambert, M., Staerk, D., Hansen, S. H., & Jaroszewski, J. W. (2005). HPLC-SPE-NMR hyphenation in natural products research: optimization of analysis of Croton membranaceus extract. Magnetic Resonance in Chemistry, 43, 771-775.
Lambert, M., Stærk, D., Hansen, S. H., Sairafianpour, M., & Jaroszewski, J. W. (2005). Rapid extract dereplication using HPLC-SPE-NMR: Analysis of isoflavonoids from Smirnowia iranica. Journal of Natural Products, 68, 1500-1509.
Lassen, P. R., Skytte, D. M., Hemmingsen, L., Nielsen, S. F., Freedman, T. B., Nafie, L. A., & Christensen, S. B. (2005). Structure and absolute configuration of nyasol and hinokiresinol via synthesis and vibrational circular dichroism spectroscopy. Journal of Natural Products, 68, 1603-1609.
Leimu, R., Riipi, M., & Stærk, D. (2005). Food preference and performance of the larvae of a specialist herbivore: Variation among and within host-plant populations. Acta Oecologica, 28, 325-330.
Madubanya, L. A., Jäger, A. K., Makunga, N. P., Geldenhuys, C. J., & van Staden, J. (2005). DNA fingerprinting and anti-inflammatory activity of Ocotea bullata bark from different locations. South African Journal of Botany, 71, 38-44.
Makunga, N. P., Jäger, A. K., & van Staden, J. (2005). An improved system for the in vitro regeneration of Thapsia garganica L. via direct organogenesis - influence of auxins and cytokinins. Plant Cell, Tissue and Organ Culture, 82, 271-280.
Olsen, C. A., Witt, M., Hansen, S. H., Jaroszewski, J. W., & Franzyk, H. (2005). Fukuyama-Mitsunobu alkylation in amine synthesis on solid phase revisited: N-alkylation with secondary alcohols and synthesis of curtatoxins. Tetrahedron, 61, 6046-6055.
Olsen, C. A., Franzyk, H., & Jaroszewski, J. W. (2005). N-alkylation reactions and indirect formation of amino functionalities in solid-phase synthesis. Synthesis, 2631-2653.
Olsen, C. A., Jørgensen, M. R., Hansen, S. H., Witt, M., Jaroszewski, J. W., & Franzyk, H. (2005). Side-chain-anchored Nα-Fmoc-Tyr-OPfp for bidirectional solid-phase synthesis. Organic Letters, 7, 1703-1706.
Reid, K. A., Jäger, A. K., Light, M. E., Mulholland, D. A., & Staden, J. V. (2005). Phytochemical and pharmacological screening of Sterculiaceae species and isolation of anticbacterial compounds. Journal of Ethnopharmacology, 97, 285-291.
Salah, S. M. & Jäger, A. K. (2005). Screening of traditionally used Lebanese herbs for neurological activities. Journal of Ethnopharmacology, 97, 145-149.
Salah, S. M. & Jäger, A. K. (2005). Two flavonoids from Artemisia herba-alba Asso with in vitro GABAA-benzodiazepine receptor activity. Journal of Ethnopharmacology, 99, 145-146.
Sandager, M., Nielsen, N. D., Stafford, G. I., van Staden, J., & Jäger, A. K. (2005). Alkaloids from Boophane disticha with affinity to the serotonin transporter in rat brain. Journal of Ethnopharmacology, 98, 367-370.
Singh, P., Mhaka, A. M., Christensen, S. B., Gray, J. J., Denmeade, S. R., & Isaacs, J. T. (2005). Applying linear interaction energy method for rational design of noncompetitive allosteric inhibitors of the sarco- and endoplasmic reticulum calcium ATPase. Journal of Medicinal Chemistry, 48, 3005-3014.
Sparg, S. G., Jäger, A. K., Magwa, M. L., & van Staden, J. (2005). Cultivating the medicinal plant Merwilla natalensis as a crop: A small-scale farming approach. Outlook on Agriculture, 34, 116-220.
Sparg, S. G., Jäger, A. K., & van Staden, J. (2005). The effect of cultivation and plant age on the pharmacological activity of Merwilla natalensis bulbs. South African Journal of Botany, 71, 191-196.
Stafford, G. I., Jäger, A. K., & van Staden, J. (2005). Activity of traditional South African sedative and potentially CNS-acting plants in the GABA-benzodiazepine receptor assay. Journal of Ethnopharmacology, 100, 210-215.
Stafford, G. I., Jäger, A. K., & van Staden, J. (2005). Effect of storage on the chemical composition and biological activity of several popular South African medicinal plants. Journal of Ethnopharmacology, 97, 107-115.
Stærk, D., Nezhad, K. B., Asili, J., Emami, S. A., Ahi, A., Sairafianpour, M., & Jaroszewski, J. W. (2005). Phenanthroindolizidine alkaloids from Vincetoxicum pumilum. Biochemical Systematics and Ecology, 33, 957-960.
Søhoel, H., Liljefors, T., Ley, S. V., Oliver, S. F., Antonello, A., Smith, M. D., Olsen, C. E., Isaacs, J. T., & Christensen, S. B. (2005). Total synthesis of two novel subpicomolar sarco/endoplasmatic reticulum Ca2+-ATPase (SERCA) inhibitors designed by an analysis of the binding site of thapsigargin. Journal of Medicinal Chemistry, 48, 7005-7011.
2004
Asili, J., Lambert, M., Ziegler, H. L., Stærk, S., Sairafianpour, M., Witt, M., Asghari, G., Ibrahimi, I. S., & Jaroszewski, J. W. (2004). Labdanes and isopimaranes from Platycladus orientalis and their effects on erythrocyte membrane and on Plasmodium falciparum growth in the erythrocyte host cells. Journal of Natural Products, 67, 631-637.
Bringmann, G., Dreyer, M., Faber, J. H., Dalsgaard, P. W., Stærk, D., Jaroszewski, J. W., Ndangalasi, H., Mbago, F., Brun, R., & Christensen, S. B. (2004). Ancistrotanzanine C and related 5,1'- and 7,3'-coupled naphthylisoquinoline alkaloids from Ancistrocladus tanzaniensis. Journal of Natural Products, 67, 743-748.
Bylov, T., Franzyk, H., & Jaroszewski, J. W. (2004). Cyclopentanoid cycanohydrin glucosides from Passiflora mixta. Biochemical Systematics and Ecology, 32, 695-698.
Duker-Eshun, G., Jaroszewski, J. W., Asomaning, W. A., Oppong-Boachie, F., & Christensen, S. B. (2004). Antiplasmodial constituents of Cajanus cajan. Phytotherapy Research, 18, 128-130.
Hansen, I., Brimer, L., & Mølgaard, P. (2004). Herbivore-deterring secondary compounds in heterophyllous woody species of the Mascarene Islands. Perspectives in Plant Ecology, Evolution and Systematics, 6, 187-203.
Janssen, S., Jakobsen, C. M., Rosen, D. M., Ricklis, R. M., Reineke, U., Christensen, S. B., Lilja, H., & Denmeade, S. R. (2004). Screening a combinatorial peptide library to develop a human glandular kallikrein 2-activated prodrug as targeted therapy for prostate cancer. Molecular Cancer Therapeutics, 3, 1439-1450.
Jaroszewski, J. W., Ekpe, P., & Witt, M. (2004). Cyclopentanoid cyanohydrin glucosides and amides of Lindackeria dentata. Planta Medica, 70, 1001-1003.
Jensen, A. A., Mikkelsen, I., Frølund, B., Frydenvang, K., Brehm, L., Jaroszewski, J. W., Bräuner-Osborne, H., Falch, E., & Krogsgaard-Larsen, P. (2004). Carbamoylcholine homologs: synthesis and pharmacology at nicotinic acetylcholine receptors. European Journal of Pharmacology, 497, 125-137.
Jäger, A. K., Adsersen, A., & Fennell, C. W. (2004). Acetylcholinesterase inhibition of Crinum sp. South African Journal of Botany, 70, 323-325.
Jäger, A. K., McGaw, L.-J., Grace, O. M., & van Staden, J. (2004). Bioprospecting of forest and woodland plant species used in zulu traditional medicine. In: Lawes, M. J., Eeley, H. A. C., Shackleton, C. M., & Geach, B. G. S., eds., Indigenous Forests and Woodlands in South Africa, Policy, People and Practice. Pietermaritzburg: University of KwaZulu-Natal Press; pp. 493-516.
Ley, S. V., Antonello, A., Balskus, E. P., Booth, D. T., Christensen, S. B., Cleator, E., Gold, H., Högenauer, K., Hünger, U., Myers, R. M., Oliver, S. F., Simic, O., Smith, M. D., Søhoel, H., & Woolford, A. J. A. (2004). Synthesis of the thapsagargins. Proceedings of the National Academy of Sciences of the United States of America, 101, 12073-12078.
Liu, H., Olsen, C. E., & Christensen, S. B. (2004). Tethered lipids from Thapsia garganica. Journal of Natural Products, 67, 1439-1440.
Nielsen, N. D., Sandager, M., Stafford, G. I., van Staden, J., & Jäger, A. K. (2004). Screening of indigenous plants from South Africa for affinity to the serotonin reuptake transport protein. Journal of Ethnopharmacology, 94, 159-163.
Olsen, C. A., Witt, M., Jaroszewski, J. W., & Franzyk, H. (2004). Diols as building blocks in solid-phase synthesis of polyamine toxins by Fukuyama-Mitsunobu alkylation. Synlett, 473-476.
Olsen, C. A., Witt, M., Jaroszewski, J. W., & Franzyk, H. (2004). Expedient protocol for solid-phase synthesis of secondary and tertiary amines. Organic Letters, 6, 1935-1938.
Olsen, C. A., Witt, M., Jaroszewski, J. W., & Franzyk, H. (2004). Solid-phase synthesis of rigid acylpolyamines using temporary N-4,4'-dimethoxytrityl protection in the presence of trityl linkers. Journal of Organic Chemistry, 69, 6149-6152.
Petersson, K., Pedersen, B. T., Stærk, D., Krogfelt, K. A., & Larsen, C. (2004). N4-alkyloxycarbonyl derivatives of cytosine: physicochemical characterisation, and cytosine regeneration rates and release from alginic acid gels. European Journal of Pharmaceutical Sciences, 23, 337-345.
Risa, A., Risa, J., Adsersen, A., Stafford, G.I., van Staden, J., & Jäger, A.K. (2004). Acetylcholinesterase inhibitory activity of plants used as memory-enhancers in traditional South African medicine. South African Journal of Botany, 70, 664-666.
Risa, J., Risa, A., Adsersen, A., Gauguin, B., Stafford, G. I., van Staden, J., & Jäger, A. K. (2004). Screening of plants used in southern Africa for epilepsy and convulsions in the GABAA-benzodiazepine receptor assay. Journal of Ethnopharmacology, 93, 177-182.
Simonsen, H. T., Adsersen, A., Bremmer, P., Heinrich, M., Smitt, U. W., & Jaroszewski, J. W. (2004). Antifungal constituents of Melicope borbonica. Phytotherapy Research, 18, 542-545.
Stærk, D., Skole, B., Jørgensen, F. S., Budnik, B. A., Ekpe, P., & Jaroszewski, J. W. (2004). Isolation of a library of aromadendranes from Landolphia dulcis and its characterization using the VolSurf approach. Journal of Natural Products, 67, 799-805.
Stærk, D., Larsen, J., Larsen, L. A., Olafsdottir, E. S., Witt, M., & Jaroszewski, J. W. (2004). Selagoline, a new alkaloid from Huperzia selago. Natural Product Research, 18, 197-203.
Uzun, E., Sariyar, G., Adsersen, A., Karakoc, B., Ötük, G., Oktayoglu, E., & Pirildar, S. (2004). Traditional medicine in Sakarya province (Turkey) and antimicrobial activities of selected speicies. Journal of Ethnopharmacology, 95, 287-296.
van Staden, J., Sparg, S. G., Light, M. E. & Jäger, A. K. (2004). A cross disciplinary approach to research and its relevance to socio-economic development. Proceedings of Global Summit on Medicinal Plants - Recent Trends in Phytomedicine and Other Alternative Therapies for Human Welfare. 271-274.
van Staden, J., Jäger, A. K., Light, M. E., & Burger, B. V. (2004). Isolation of the major germination cue from plant-derived smoke. South African Journal of Botany, 70, 654-659.
Ziegler, H. L., Franzyk, H., Sairafianpour, M., Tabatabai, M., Tehrani, M. D., Bagherzadeh, K., Hägerstrand, H., Stærk, D., & Jaroszewski, J. W. (2004). Erythrocyte membrane modifying agents and the inhibition of Plasmodium falciparum growth: structure-activity relationships for betulinic acid analogues. Bioorganic & Medicinal Chemistry, 12, 119-127.
Ziegler, H. L., Hansen, S. H., Stærk, D., Christensen, S. B., Hägerstrand, H., & Jaroszewski, J. W. (2004). The antiparasitic compound licochalcone A is a potent echinocytogenic agent that modifies the erythrocyte membrane in the concentration range where antiplasmodial activity is observed. Antimicrobial Agents and Chemotherapy, 48, 4067-4071.
2003
Agerbirk, N., Olsen, C. E., Bibby, B. M., Frandsen, H. O., Brown, L. D., Nielsen, J. K., & Rennwick, J. A. A. (2003). A saponin correlated with variable resistance of Barbarea vulgaris to the diamondback moth Plutella xylostella. Journal of Chemical Ecology, 29, 1417-1433.
Brier, T. J., Mellor, I. R., Tikhonov, D. B., Neagoe, I., Shao, Z. Y., Brierley, M. J., Strømgaard, K., Jaroszewski, J. W., Krogsgaard-Larsen, P., & Usherwood, P. N. R. (2003). Contrasting actions of philanthotoxin-343 and philanthotoxin-(12) on human muscle nicotinic acetylcholine receptors. Molecular Pharmacology, 64, 954-964.
Bringmann, G., Dreyer, M., Faber, J., Dalsgaard, P. W., Stærk, D., Jaroszewski, J. W., Ndangalasi, H., Mbago, F., Brun, R., Reichert, M., Maksimenka, K., & Christensen, S. B. (2003). Anzistrotanzanine A, the first 5,3'-coupled naphtylisoquinoline alkaloid and two further 5,8'-linked related compounds from the newly described species Ancistrocladus tanzaniensis. Journal of Natural Products, 66, 1159-1165.
Denmeade, S. R., Jakobsen, C. M., Janssen, S., Khan, S. R., Garrett, E. S., Lilja, H., Christensen, S. B., & Isaacs, J. T. (2003). Prostate-specific antigen-activated thapsigargin prodrug as targeted therapy for prostate cancer. Journal of the National Cancer Institute, 95, 990-1000.
Grace, O. M., Prendergast, H. D. V., van Staden, J., & Jäger, A. K. (2003). The suitability of thin layer chromatography for authenticating bark medicines used in South African traditional healthcare. South African Journal of Botany, 69, 165-169.
Jäger, A. K. (2003). Evaluation of antibacterial activity of traditionally prepared South African remedies for infection. South African Journal of Botany, 69, 595-598.
Kirk, L. F., Møller, M. V., Christensen, J., Stærk, D., Ekpe, P., & Jaroszewski, J. W. (2003). A 5-deoxyflavonol derivative in Mimosa pudica. Biochemical Systematics and Ecology, 31, 103-105.
Larsen, E., Kharazmi, A., Christensen, L. P., & Christensen, S. B. (2003). An antiinflammatory galactolipid from rose hip (Rosa canina L.) that inhibits chemotaxis of human peripheral blood neutrophils in vitro. Journal of Natural Products, 66, 994-995.
Lindsey, K. L., Viljoen, A., & Jäger, A. K. (2003). Screening of Aloes for antioxidant activity. South African Journal of Botany, 69, 599-602.
Makunga, N. P., Jäger, A. K., & van Staden J. (2003). Micropropagation of Thapsia garganica - a medicinal plant. Plant Cell Reports, 21, 967-973.
Mellor, I. R., Brier, T. J., Pluteanu, F., Strømgaard, K., Saghyan, A., Eldursi, N., Brierley, M. J., Andersen, K., Jaroszewski, J. W., Krogsgaard-Larsen, P., & Usherwood, P. N. R. (2003). Modification of the philanthotoxin-343 polyamine moiety results in different structure-activity profiles at muscle nicotinic ACh, NMDA and AMPA receptors. Neuropharmacology, 44, 70-80.
Motsei, M. L., Lindsey, K. L., van Staden, J., & Jäger, A. K. (2003). Screening of some South African plants for antifungal activity against Candida albicans. Journal of Ethnopharmacology, 86, 235-241.
Mølgaard, P., Johnsen, S., Christensen, P., & Cornett, C. (2003). HPLC method validated for the simultaneous analysis of cichoric acid and alkamides in Echinacea pupurea plants and products. Journal of Agricultural and Food Chemistry, 51, 6922-6933.
Ndekha, A., Hansen, E. H., Mølgaard, P., Woelk, G., & Furu, P. (2003). Community participation as an interactive learning process: Experiences from a schistosomiasis control project in Zimbabwe. Acta Tropica, 85, 325-338.
Olsen, C. A., Witt, M., Jaroszewski, J. W., & Franzyk, H. (2003). Solid-phase polyamine synthesis using piperazine and piperidine building blocks. Organic Letters, 5, 4183-4185.
Olsen, C. A., Jørgensen, M. R., Witt, M., Mellor, I. R., Usherwood, P. N. R., Jaroszewski, J. W., & Franzyk, H. (2003). The choice of phosphane reagent in Fukuyama-Mitsunobu alkylation: Intramolecular selectivity between primary and secondary alcohols in the preparation of asymmetric tetraamine building blocks for synthesis of philanthotoxins. European Journal of Organic Chemistry, 3288-3299.
Rønsted, N., Franzyk, H., Mølgaard, P., Jaroszewski, J. W., & Jensen, S. R. (2003). Chemotaxonomy and evolution of Plantago L. Plant Systematics and Evolution, 242, 63-82.
Sairafianpour, M., Bahreininejad, B., Witt, M., Ziegler, H. L., Jaroszewski, J. W., & Stærk, D. (2003). Terpenoids of Salvia hydrangea: Two new, rearranged 20-norabietanes and the effect of oleanolic acid on erythrocyte membranes. Planta Medica, 69, 846-850.
Simonsen, H. T., Adsersen, A., Smitt, U. W., Strasberg, D., & Jaroszewski, J. W. (2003). Methoxyflavones from Melicope borbonica and M. obscura (Rutaceae). Biochemical Systematics and Ecology, 31, 327-330.
Stærk, D., Witt, M., Oketch-Rabah, H., & Jaroszewski, J. W. (2003). A new class of spermidine-derived alkaloids. Organic Letters, 5, 2793-2796.
Wellendorph, P., Jaroszewski, J. W., Hansen, S. H., & Franzyk, H. (2003). A sequential high-yielding large-scale solution-method for synthesis of philanthotoxin analogues. European Journal of Medicinal Chemistry, 38, 117-122.
2002
Arthur, G. D., Jäger, A. K., & van Staden, J. (2002). Uptake of [3H]DHZ by tomato seedlings. South African Journal of Botany, 67, 661-666.
Ballin, N. Z., Traore, M., Tinto, H., Sittie, A., Mølgaard, P., Olsen, C. E., Kharazmi, A., & Christensen, S. B. (2002). Antiplasmodial compounds from Cochlospermum tinctorium. Journal of Natural Products, 65, 1325-1327.
Christensen, S. B., Franzyk, H., Frølund, B., Jaroszewski, J. W., Stærk, D., & Vedsø, P. (2002). Incorporation of the CrossFire Beilstein database in the organic chemistry curriculum at the Royal Danish School of Pharmacy. Journal of Chemical Education, 79, 765-768.
Clausen, V., Frydenvang, K., Koopmann, R., Jørgensen, L. B., Abbiw, D. K., Ekpe, P., & Jaroszewski, J. W. (2002). Plant analysis by butterflies: Occurrence of cyclopentenylglycines in Passifloraceae, Flacourtiaceae, and Turneraceae and discovery of the novel nonproteinogenic amino acid 2-(3'-cyclopentenyl)glycine in Rinorea. Journal of Natural Products, 65, 542-547.
Duker-Eshun, G., Jaroszewski, J. W., Asomaning, W. A., Oppong-Boachie, F., Olsen, C. E., & Christensen, S. B. (2002). Antiplasmodial activity of labdanes from Aframomum latifolium and Aframomum sceptrum. Planta Medica, 68, 642-644.
Friis-Møller, A., Chen, M., Fuursted, K., Christensen, S. B., & Kharazmi, A. (2002). In vitro antimycobacterial and antilegionella activity of licochalcone A from chinese licorice roots. Planta Medica, 68, 416-419.
Geissler, P. W., Harris, S. A., Prince, R. J., Olsen, A., Odhiambo, R. A., Oketch-Rabah, H., Madiega, P. A., Adsersen, A., & Mølgaard, P. (2002). Medicinal plants used by Luo mothers and children in Bondo district, Kenya. Journal of Ethnopharmacology, 83, 39-54.
Grace, O. M., Light, M. E., Lindsey, K. L., Mulholland, D. A, van Staden, J. & Jäger, A. K. (2002). Antibacterial activity and isolation of active compounds from fruit of the traditional African medicinal tree Kigelia africana. South African Journal of Botany, 68, 220-222.
Grace, O. M., Prendergast, H. D. V., van Staden, J. & Jäger, A. K. (2002). Bark medicines used in traditional healthcare in KwaZulu-Natal, South Africa - an inventory. South African Journal of Botany, 69, 301-363
Grace, O. M., Prendergast, H. D. V., van Staden, J. & Jäger, A. K. (2002). The status of bark in South African traditional healthcare. South African Journal of Botany, 68, 21-30.
Jaroszewski, J. W., Olafsdottir, E. S., Wellendorph, P., Christensen, J., Franzyk, H., Somanadhan, B., Budnik, B. A., Jørgensen, L. B., & Clausen, V. (2002). Cyanohydrin glycosides of Passiflora: distribution pattern, a saturated cyclopentane derivative from P. guatemalensis, and formation of pseudocyanogenic α-hydroxyamides as isolation artefacts. Phytochemistry, 59, 501-511.
Jensen, H. D., Krogfelt, K. A., Cornett, C., Hansen, S. H., & Christensen, S. B. (2002). Hydrophilic carboxylic acids and iridoid glycosides in the juice of american and european cranberries (Vaccinium macrocarpon and V. oxycoccus), loganberries (V. vitis-idaea), and blueberries (V. myrtillus). Journal of Agricultural and Food Chemistry, 50, 6871-6874.
Jensen, J. F., Kvist, L. P., & Christensen, S. B. (2002). An antiplasmodial lignan from Euterpe precatoria. Journal of Natural Products, 65, 1915-1917.
Jäger, A. K., & van Staden, J. (2002). Soluble sugars in light-sensitive Grand Rapids lettuce seeds treated with red light, gibberellic acid and a plant-derived smoke extract. South African Journal of Botany, 68, 404-407.
Kromann, H., Krikstolaityte, S., Andersen, A. J., Andersen, K., Krogsgaard-Larsen, P., Jaroszewski, J. W., Egebjerg, J., & Strømgaard, K. (2002). Solid-phase synthesis of polyamine toxin analogues, potent and selective antagonists of Ca2+-permeable AMPA receptors. Journal of Medicinal Chemistry, 45, 5745-5754.
Light, M. E., Gardner, M. J., Jäger, A. K., & van Staden, J. (2002). Dual regulation of seed germination by smoke solutions. Plant Growth Regulation, 37, 135-141.
Light, M. E., McGaw, L. J., Rabe, T., Sparg, S. G., Taylor, M. B., Erasmus, D. G., Jäger, A. K., & van Staden, J. (2002). Pharmacological activity of Siphonochilus aethiopicus. South African Journal of Botany, 68, 55-61.
Light, M. E., McGaw, L. J., Sparg, S. G., Jäger, A. K., & van Staden, J. (2002). Screening of Cenchrus ciliaris L. for biological activity. South African Journal of Botany, 68, 411-413.
Lindsey, K. L., Jäger, A. K., & Viljoen, A. (2002). Cyclooxygenase inhibitory activity of Aloes. South African Journal of Botany, 68, 47-50.
Lindsey, K. L., Motsei, M. L., & Jäger, A. K. (2002). Screening of Southern African food plants for antioxidant activity. Journal of Food Science, 67, 2129-2131.
McGaw, L. J., Jäger, A. K., & van Staden, J. (2002). Antibacterial effects of fatty acids from plants. South African Journal of Botany, 68, 417-423.
McGaw, L. J., Jäger, A. K., & van Staden, J. (2002). Antibacterial fatty acids from Schotia brachypetala. Fitoterapia, 73, 431-433.
McGaw, L. J., Jäger, A. K., & van Staden, J. (2002). Isolation of β-asarone, an antibacterial and anthelmintic compound, from Acorus calamus in South Africa. South African Journal of Botany, 68, 31-35.
McGaw, L. J., Jäger, A. K., & van Staden, J. (2002). Variation in antibacterial activity of Schotia species. South African Journal of Botany, 68, 41-46.
Olafsdottir, E. S., Bolt-Jørgensen, L., & Jaroszewski, J. W. (2002). Cyanogenesis in glucosinolate-producing plants: Carica papaya and Carica quercifolia. Phytochemistry, 60, 269-273.
Rønsted, N., Strandgaard, H., Jensen, S. R., & Mølgaard, P. (2002). Chlorogenic acid from three species of Hydrostachys. Biochemical Systematics and Ecology, 30, 1105-1108.
Rønsted, N., & Jensen, S. R. (2002). Iridoid glucosides and caffeoyl phenylethanoid glycosides from Campylanthus salsaloides and Campylanthus glaber. Biochemical Systematics and Ecology, 30, 1091-1095.
Rønsted, N., Chase, M. W., Albach, D. C., & Bello, M. A. (2002). Phylogenetic relationships within Plantago (Plantaginaceae): evidence from nuclear ribosomal ITS and plastid trnL-F sequence data. Botanical Journal of the Linnean Society, 139, 323-338.
Sairafianpour, M., Kayser, O., Christensen, J., Asfa, M., Witt, M., Stærk, D., & Jaroszewski, J. W. (2002). Leishmanicidal and antiplasmodial activity of constituents of Smirnowia iranica. Journal of Natural Products, 65, 1754-1758.
Simonsen, H. T., Larsen, M. D., Nielsen, M. W., Adsersen, A., Olsen, C. E., Strasberg, D., Smitt , U. W., & Jaroszewski, J. W. (2002). Methylenedioxy- and methoxyflavones from Melicope coodeana syn. Euodia simplex. Phytochemistry, 60, 817-820.
Sparg, S. G., van Staden, J., & Jäger, A. K. (2002). Pharmacological and phytochemical screening of two Hyacinthaceae species, Scilla natalensis and Ledebouria ovatifolia. Journal of Ethnopharmacology, 80, 95-101.
Strømgaard, K., Mellor, I. R., Andersen, K., Neagoe, I., Pluteanu, F., Usherwood, P. N., Krogsgaard-Larsen, P., & Jaroszewski, J. W. (2002). Solid-phase synthesis and pharmacological evaluation of analogues of PhTX-12 - a potent and selective nicotinic acetylcholine receptor antagonist. Bioorganic & Medicinal Chemistry Letters, 12, 1159-1162.
Stærk, D., Lykkeberg, A. K., Christensen, J., Budnik, B. A., Abe, F., & Jaroszewski, J. W. (2002). In vitro cytotoxic activity of phenanthroindolizidine alkaloids from Cynanchum vincetoxicum and Tylophora tanakae against drug-sensitive and multidrug-resistant cancer cells. Journal of Natural Products, 65, 1299-1302.
Tetyana, P., Prozesky, E. A., Jäger, A. K., Meyer, J. J. M., & van Staden, J. (2002). Some medicinal properties of Cussonia species used in traditional medicine. South African Journal of Botany, 68, 51-54.
Yff, B. T. S., Lindsey, K. L., Taylor, M. B., Erasmus, D. G., & Jäger, A. K. (2002). The pharmacological screening of Pentanisia prunelloides and the isolation of the anti-bacterial compound palmitic acid. Journal of Ethnopharmacology, 79, 101-107.
Ziegler, H. L., Stærk, D., Christensen, J., Hviid, L., Hägerstrand, H., & Jaroszewski, J. W. (2002). In vitro Plasmodium falciparum drug sensitivity assay: Inhibition of parasite growth by incorporation of stomatocytogenic amphiphiles into the erythrocyte membrane. Antimicrobial Agents and Chemotherapy, 46, 1441-1446.
Ziegler, H. L., Stærk, D., Christensen, J., Olsen, C. E., Sittie, A. A., & Jaroszewski, J. W. (2002). New dammarane and malabaricane triterpenes from Caloncoba echinata. Journal of Natural Products, 65, 1764-1768.
Ziegler, H. L., Jensen, T. H., Christensen, J., Stærk, D., Hägerstrand, H., Sittie, A. A., Olsen, C. E., Staalsø, T., Ekpe, P., & Jaroszewski, J. W. (2002). Possible artefacts in the in vitro determination of antimalarial activity of natural products that incorporate into lipid bilayer: Apparent antiplasmodial activity of dehydroabietinol, a constituent of Hyptis suaveolens. Planta Medica, 68, 547-549.
2001
Andersen, L., Clausen, V., Oketch-Rabah, H. A., Lechtenberg, M., Adsersen, A., Nahrstedt, A., & Jaroszewski, J. W. (2001). Gynocardin and cyclopentenylglycine in Rawsonia lucida. Biochemical Systematics and Ecology, 29, 219-222.
Chen, M., Zhai, L., Christensen, S. B., Theander, T., & Kharazmi, A. (2001). Inhibition of fumarate reductase in Leishmania major and L. donovani by chalcones. Antimicrobial Agents and Chemotherapy, 45, 2023 - 2029.
Christensen, J., & Jaroszewski, J. W. (2001). Natural glycosides containing allopyranose from the passion fruit plant and circular dichroism of benzaldehyde cyanohydrin glycosides. Organic Letters, 3, 2193-2195.
Christensen, S. B., & Kharazmi, A. (2001). Antimalarial natural products. In: Tringali, C., ed., Bioactive Compounds from Natural Sources: Isolation, Characterization and Biological Properties. London: Taylor & Francis; pp. 381-431.
Clausen, V., Wellendorph, P., Ekpe, P., & Jaroszewski, J. W. (2001). Tetraphyllin B, volkenin and cyclopentenylglycine in Androsiphonia adenostegia. Biochemical Systematics and Ecology, 29, 317-319.
Jakobsen, C. M., Denmeade, S. R., Isaacs, J. T., Gady, A., Olsen, C. E., & Christensen, S. B. (2001). Design, synthesis, and pharmacological evaluation of thapsigargin analogues for targeting apoptosis to prostatic cancer cells. Journal of Medicinal Chemistry, 44, 4696-4703.
Jacobsen, T. H., Marcussen, H. V., Adsersen, A., Strasberg, D., Smitt, U. W., & Jaroszewski, J. W. (2001). 3-Methoxyflavones and a novel coumarin from Psiadia dentata (Cass.) DC. Biochemical Systematics and Ecology, 29, 963-965.
Nielsen, P. A., Jaroszewski, J. W., Norrby, P.-O., & Liljefors, T. (2001). An NMR and ab initio quantum chemical study of acid-base equilibria for conformationally constrained acidic α-amino acids in aqueous solution. Journal of the American Chemical Society, 123, 2003-2006.
Olafsdottir, E. S., Omarsdottir, S., & Jaroszewski, J. W. (2001). Constituents of three Icelandic Alchemilla species. Biochemical Systematics and Ecology, 29, 959-962.
Sairafianpour, M., Christensen, J., Stærk, D., Budnik, B. A., Kharazmi, A., Bagherzadeh, K., & Jaroszewski, J. W. (2001). Leishmanicidal, antiplasmodial and cytotoxic activity of novel diterpenoid 1,2-quinones from Perovskia abrotanoides: New source of tanshinones. Journal of Natural Products, 64, 1398-1403.
Strømgaard, K., Andersen, K., Ruhland, T., Krogsgaard-Larsen, P., & Jaroszewski, J. W. (2001). A versatile method for solid phase synthesis of polyamines: Neuroactive polyamine toxins as example. Synthesis, 877-884.
Strømgaard, K., Andersen, K., Krogsgaard-Larsen, P., & Jaroszewski, J. W. (2001). Recent advances in the medicinal chemistry of polyamine toxins. Mini Reviews in Medicinal Chemistry, 1, 317-338.
Stærk, D., Norrby, P.-O., & Jaroszewski, J. W. (2001). Conformational analysis of indole alkaloids corynantheine and dihydrocorynantheine by dynamic 1H NMR spectroscopy and computational methods: Steric effect of ethyl vs. vinyl group. Journal of Organic Chemistry, 66, 2217-2221.
Sørensen, U. S., Falch, E., Stensbøl, T. B., Jaroszewski, J. W., Madsen, U., & Krogsgaard-Larsen, P. (2001). Structural determinants for AMPA agonist activity of aryl or heteroaryl sybstituted AMPA analogues - synthesis and pharmacology. Archiv der Pharmazie, 334, 62-68.
Wellendorph, P., Clausen, V., Jørgensen, L. B., & Jaroszewski, J. W. (2001). Cyclopentanoids of Mathurina penduliflora. Biochemical Systematics and Ecology, 29, 649-651.
2000
Andersen, L., Nielsen, B., & Jaroszewski, J. W. (2000). Synthesis of epimers of L-cyclopentenylglycine using enzymatic resolution. Chirality, 12, 665-669.
Kreilgaard, M., Pedersen, E. J., & Jaroszewski, J. W. (2000). NMR characterisation and transdermal drug delivery potential of microemulsion systems. Journal of Controlled Release, 69, 421-433.
Moesgaard, B., Petersen, G., Jaroszewski, J. W., & Hansen, H. S. (2000). Age dependent accumulation of N-acyl-ethanolamine phospholipids in ischemic rat brain: A 31P NMR and enzyme activity study. Journal of Lipid Research, 41, 985-990.
Rasmussen, H. B., Christensen, S. B., Kvist, L. P., & Kharazmi, A. (2000). A simple and efficient separation of the curcumins, the antiprotozoal constituents of Curcuma longa. Planta Medica, 66, 396-398.
Rasmussen, H. B., Christensen, S. B., Kvist, L. P., Kharazmi, A., & Huansi, A. G. (2000). Absolute configuration and antiprotozoal activity of minquartynoic acid. Journal of Natural Products, 63, 1295-1296.
Rønsted, N., Gobel, E., Franzyk, H., Jensen, S. R., & Olsen, C. E. (2000). Chemotaxonomy of Plantago - iridoid glucosides and caffeoyl phenylethanoid glycosides. Phytochemistry, 55, 337-348.
Smith, L., Andersen, K. B., Hovgaard, L., & Jaroszewski, J. W. (2000). Rational selection of antisense oligonucleotide sequences. European Journal of Pharmaceutical Sciences, 11, 191-198.
Strømgaard, K., Brier, T. J., Andersen, K., Mellor, I. R., Saghyan, A., Tikhonov, D., Usherwood, P. N. R., Krogsgaard-Larsen, P., & Jaroszewski, J. W. (2000). Solid phase synthesis and biological evaluation of a combinatorial library of philanthotoxin analogues. Journal of Medicinal Chemistry, 43, 4526-4533.
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