Susan Weng Larsen

Scientific Career

Assistant Professor, Department of Pharmaceutics and Analytical Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, 2003.
PhD, Department of Pharmaceutics, The Danish University of Pharmaceutical Sciences, 2003.
MSc (pharmacy), The Danish University of Pharmaceutical Sciences, 1998.

Research Interests

Design of innovative parenteral depot formulations with focus on intra-articular injection.
In vitro release methods for investigation of drug release from controlled release parenterals.
Prodrug design and salt formation.
Pharmaceutical Preformulation. Physical chemical characterization and stability assessment of drug substances.

Teaching

(Danish only)
Physical Chemistry
Physical Chemistry, Laboratory Course
Pharmaceutical Preformulation
Chemical Reactivity and Stability of Drugs
Drug Formulation
Drug Formulation, Laboratory Course

Supervision

Theses in Danish
Theses in English

Publications

Publications 2007 - present
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2006 - 1997
Larsen, S.W; Østergaard, J; Friberg-Johansen, H; Jessen, M.N.B; Larsen, C.
In vitro assessment of drug release rates from oil depot formulations intended for intra-articular administration.
Eur. J. Pharm. Sci. 29, 348-345. 2006.
Østergaard, J; Larsen, S.W; Parshad, H; Larsen, C.
Bupivacaine salts of diflunisal and other aromatic hydroxycarboxylic acids : aqueus solubility and release characteristics from solutions and suspensions using a rotating dialysis cell model.
Eur. J. Pharm. Sci. 26, 280-287. 2005.
Pedersen, B.T; Østergaard, J; Larsen, S.W; Larsen, C.
Characterization of the rotating dialysis cell as an in vitro model potentially useful for simulation of the pharmacokinetic fate of intra-articularly administered drugs.
Eur. J. Pharm. Sci. 25, 73-79. 2005.
Larsen, S.W; Ankersen, M; Larsen, C.
Kinetics of degradation and oil solubility of ester prodrugs of a model dipeptide (Gly-Phe).
Eur. J. Pharm. Sci. 22, 399-408. 2004.
Larsen, C; Larsen, S.W; Østergaard J; Pedersen B.T.
Dansk patentansøgning (PA 2003 01748) Drug-containing vehicles for local administration of active drug substances.
Larsen, S.W; Sidenius, M; Ankersen, M; Larsen, C.
Kinetics of degradation of 4-imidazolidinone prodrug types obtained from reacting prilocaine with formaldehyde and acetaldehyde.
Eur. J. Pharm. Sci. 20, 233-240. 2003.
Larsen, S.W; Rinvar, E; Svendsen, O; Lykkesfeldt, J; Friis, G.J; Larsen, C.
Determination of the disappearance rate of iodine-125 labelled oils from the injection site after intramuscular and subcutaneous administration to pigs.
Int. J. Pharm. 230, 67-75. 2001.
Larsen, S.W; Thomsen, A.E; Rinvar, E; Friis, G.J; Larsen, C.
Effect of drug lipophilicity on in vitro release rate from oil vehicles using nicotinic acid esters as model prodrug derivatives.
Int. J. Pharm. 216, 83-93. 2001.
Fredholt, K; Adrian, C; Just, L; Larsen, D.H; Weng, S; Moss, B; Friis, G.J.
Chemical and enzymatic stability as well as transport properties of a Leu-enkephalin analogue and ester prodrugs thereof.
J. Control. Release 63, 261-273. 2000.
Sørensen, L; Weng, S; Weng, S.L; Wulf-Andersen; L., Østergaard, D; Bech, P.G. The costs of asthma in Denmark.
Br. J. Medical Economics 11, 103-111. 1997.